PSL Physiology Courses
Credit course for supervised participation in faculty research project. See page 40 for details.
Principles of respiratory, cardiovascular, gastrointestinal, renal and reproductive physiology for students enroled in the Neuroscience program.
Principles of Human Physiology with tutorials on the biophysical concepts applied to physiological processes. Restricted to students enroled in the Biophysics and Physiology (Theoretical) programs
Using homeostasis and feedback as a unifying theme, topics in control systems, cell signalling, rhythms, environmental adaptations and body weight regulations are examined. Tutorials use computer simulations and problem sets.
A problem-based laboratory course focussed on the integration of organ systems to understand the control mechanisms of body function.
This course provides an in-depth review of the development and function of the male and female reproductive systems. Topics include sex determination and differentiation, gametogenesis, hormonal control of the reproductive systems, the female ovulatory cycle, seasonal breeding, sexual behaviour, fertilization and implantation.
General overview of the integrated physiologic events associated with pregnancy and birth. The approach emphasizes physiologic processes using insights gained from studies of humans, animals, cells and genes. Where appropriate the clinical consequences of aberrant development are reviewed.
Selected topics in the fields of neuroendocrinology, steroid endocrinology and the regulation of energy metabolism illustrate the general principles underlying the control of complex endocrine systems. Particular emphasis is placed on the evolutionary development of hormone systems through gene duplication and differentiation.
This course integrates the newest findings and experimental approaches from cellular and molecular biology into metabolic function at the tissue, organ and whole body level.
General computer and mathematical techniques applied to physiology. FORTRAN/BASIC programming, solution of ordinary differential equations, curve fitting, linear systems analysis.
Theoretical treatment of physiology. Mathematical modelling and advanced analysis of physiological systems.
Math of neurons, synapses, neural networks in brain. Comparison with experimental results. Labs for simulations. Two streams, marked appropriately: Biol-advantaged, Math-acquired (paper presentations) and Math-advantaged, Biol-acquainted (probsets)
Introduction to systems neuroscience. A review of basic neuroanatomy and physiology followed by in-depth study of selected sensory and motor systems. Students with an elementary neuroscience background progress to reading neuroscience literature on their own.
Control of body movement and posture by the nervous system in normal and pathological conditions. Topics include nonlinear dynamical systems, central pattern generators in the cerebral cortex, brainstem and spinal cord, reflexes, and basal ganglia-cerebellar function.
Overview of the fundamentals of cellular and molecular aspects of brain function. Course material is updated yearly to reflect the rapid evolution of ideas in Neuroscience.
Biophysics and molecular biology of ion channels. Topics include equivalent circuits for cells, molecular structure of voltage-gated channels, distribution of channels, relationship between single-channel and whole-cell recording and regulation of channel function by voltage, phosphorylation, G-proteins and metabolites.
A practical approach to instrumentation as a preparation for using sophisticated measurement systems.
An overview of the ways in which techniques in molecular biology are being used to resolve current issues in physiology. The systems to be studied include individual cells, organ systems, integrated systems, and whole animal physiology and pathophysiology.
Heart anatomy and development, ion channels and contractile proteins involved in cardiac and smooth muscle contraction are studied. Emphasis is on regulation of electrical and contractile function of kinases, metabolism, volume and ions.
Development of the cardiovascular system from conception to adulthood with particular emphasis on maturational changes, age-related differences and developmental problems from cellular/molecular to whole organ/system.
In-depth study of specific topics in human physiological response to conditions such as altitude, cold, exercise and birth. Students are required to make field trips to physiological laboratories on campus and at the Defence and Civil Institute of Environmental Medicine.
An in-depth analysis of the basic physiology underlying sleep and circadian rhythms, and of their impact on important physiological processes, of which effects on cardio-respiratory systems are emphasized.
Students learn to read, write and speak about current research in Physiology.
Laboratory research project with reading assignments leading to a final report. By special arrangement with a Physiology staff member after admission to course. PSL498Y1 is recommended for students applying to the Physiology graduate program.
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