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CHM Chemistry CoursesSCI199Y1
Undergraduate seminar that focuses on specific ideas, questions, phenomena or controversies, taught by a regular Faculty member deeply engaged in the discipline. Open only to newly admitted first year students. It may serve as a distribution requirement course; see page 40. NOTE: CHM138H1
and 139H1 may be taken in either order, and not
in the same session. CHM138H1
An introduction to principles of structure and their relation to reactivity of organic molecules, molecular structure, stereochemistry, functional groups, and reactions. Recommended for students in life and health science programs. NOTE: CHM138H1 and 139H1 may be taken in either order, and not in the same session. CHM139H1
Recommended for students in life and health science programs. Structure of matter, gases, liquids and solids; phase equilibria and phase diagrams; colligative properties; chemical equilibria; electrolyte solutions and electrochemistry; reaction kinetics; introduction to thermodynamics. CHM151Y1
Strongly recommended for students interested in following specialist or major programs in Chemistry, and/or whose fields of study include a significant amount of chemistry. The aim of this course is to provide students with a foundation in fundamental chemical knowledge. Through examples, students will also be introduced to some exciting current areas of chemistry, including the development of new characterization techniques such as atomic resolution microscopy, the design of organic compounds, and the properties and potential uses of advanced materials. CHM200Y1
Not offered in 2003-04. CHM217H1
Introduction to classical and instrumental analytical chemistry. Scope of analytical chemistry: statistical methods; signal response, sensitivity and limit-of-detection of various techniques. Solution equilibrium applications: gravimetry, titrimetry, acid-base, redox and complexometric processes. Absorption spectroscopy: Beer’s Law CHM220H1
Introduction to thermodynamics; phase equilibrium, chemical equilibrium, electrochemistry; introduction to quantum mechanics and spectroscopy. CHM221H1
Intended as a continuation of CHM220H1 for students wishing to take some additional material in Physical Chemistry. The course covers topics in quantum mechanics and spectroscopy as well as an introduction to reaction kinetics. CHM225Y1
Directed to students in the Chemistry major and specialist programs. Topics: introductory thermodynamics, first and second law and applications; chemical equilibrium; electrochemistry, surface chemistry; chemical kinetics; introductory quantum mechanics; spectroscopy, and molecular photophysics. ENV235Y1
(see “ENV: Division of the Environment”) CHM238Y1
The first part (with CHM338H1) of a two-year sequence in Inorganic Chemistry, designed to illustrate and systematize the rich variety of structures, physical properties and reactions of compounds of the elements across and down the Periodic Table. Introduction to structure, symmetry and bonding of molecules and lattices; acid-base and redox reactions; d-metal complexes; systematic chemistry of metals and elements of the s and p blocks; inorganic materials and solid state chemistry with applications in advanced technologies. The laboratory runs weekly from January to April. CHM247H1
Reactions of organic compounds. Principles of mechanism, synthesis, and spectroscopy, continuing from CHM138H1. Tutorial (12T) is optional. CHM249H1
An in-depth survey of organic molecules and principles of their reactions. Emphasis is on understanding of the basics with respect to structure and bonding, and application of reactions to the synthesis of medicinally and industrially important compounds. This course continues from CHM151Y1 and is designed for students in the Chemistry specialist and major programs. CHM299Y1
Credit course for supervised participation in faculty research project. See page 40 for details. CHM310H1
Major chemical pollutants and their sources, the environmental reactions they undergo, and how they become distributed throughout the environment. Focus is on the principal routes of chemical and biological degradation of toxicants; oxidation, photodegradation, hydrolysis, reduction, biotic metabolism, and microbial degradation. The principal physical processes by which chemicals move, concentrate, and dissipate. CHM314Y1
Scope of instrumental analytical chemistry; Fourier transform IR absorption spectroscopy; molecular luminescence; emission spectroscopy; mass spectroscopy, electrochemical techniques; sensors; gas and high performance liquid chromatography; instrument design principles and applications in industry and the environment. The laboratory runs weekly from January to April. CHM325H1
Fashioned to illustrate how inorganic and polymer materials chemistry can be rationally used to synthesize superconductors, metals, semiconductors, ceramics, elastomers, thermoplastics, thermosets and polymer liquid crystals, with properties that can be tailored for applications in a range of advanced technologies. Coverage is fairly broad and is organized to crosscut many aspects of the field. CHM326H1
This course introduces the postulates of quantum mechanics to develop the fundamental framework of quantum theory. A number of exactly soluble problems are treated in detail as examples. Perturbation theory is introduced in the context of understanding many body problems. Various applications to molecular spectroscopy and dynamics are covered in detail. CHM328H1
This course explores the microscopic description of macroscopic phenomena in chemistry. Statistical mechanics is introduced as the bridge between the microscopic and macroscopic views, and applied to a variety of chemical problems including reaction dynamics. More advanced topics in thermodynamics are introduced and discussed as required. CHM338H1
Further study of the structures, physical properties and reactions of compounds of the main group elements and the transition metals. Introductions to spectroscopy and structural analysis, reaction mechanisms, d- and f- block organometallic compounds, catalysis, structures of solids and bioinorganic chemistry. The weekly laboratory demonstrates aspects of transition metal chemistry. CHM345H1
An overview of the preparation of various classes of organic compounds. Strategies and tactics of synthetic organic chemistry using examples from natural products and pharmaceuticals. C-C bond formation, functional group reactivity, structure, stereochemistry and selectivity. (This course is not allowed for students in any of the Chemistry specialist and major programs; they should consider CHM346H1 instead.) CHM346H1
An overview of the preparation of various classes of organic compounds. Strategies and tactics of synthetic organic chemistry using examples from natural products and pharmaceuticals. C-C bond formation, functional group reactivity, structure, stereochemistry and selectivity. (Students who are not in one of the Chemistry specialist or major programs should consider taking CHM345H1 instead of this course.) CHM347H1
An organic chemical approach to the structure and reactions of major classes of biological molecules: carbohydrates, amino acids, peptides and proteins, phosphates, lipids, heterocycles, vitamins, nucleotides and polynucleotides. This is achieved through studies of advanced stereochemistry, chemical modification, reactions and synthesis. In addition to lectures and reading from texts, there will be independent written assignments on more advanced topics. CHM348H1
Analysis of structure and reactions of organic molecules in terms of physical principles. Mechanisms of important classes of organic reactions. CHM379H1
This course provides an opportunity to learn core techniques in biological chemistry in a small group laboratory setting. Lectures will discuss the theory behind the techniques and highlight how they are used in current biological chemistry research and practice. CHM398H0/399Y0
An instructor-supervised group project in an off-campus setting. See page 40 for details. CHM409Y1
An experimental or theoretical research problem under the supervision of a member of staff. Applications for enrolment should be made to the Department in the preceding Winter Session. CHM410H1
An analytical theory, instrumental, and methodology course focused on the measurement of pollutants in soil, water, air, and biological tissues and the determination of physical/chemical properties including vapour pressure, degradation rates, partitioning. CHM414H1
Current research in analytical chemistry with emphasis on rapidly emerging techniques. Course topics chosen from biosensor technology, transducer theory and operation, device design and fabrication, surface modification and methods of surface analysis, flow injection analysis and chemometrics. CHM415H1
This course considers the chemistry occuring in the Earth’s atmosphere, with emphasis on developing molecular-level understanding of the photochemistry, free-radical kinetics, and heterogeneous chemistry that occurs. Topics include stratospheric ozone depletion, trace gas oxidation, urban air pollution, acid rain, and the connections between aerosols and climate. CHM416H1
Principles of separation in analytical chemistry. Fractionation processes
and solvent extractions; theory of chromatography, retention time, column
efficiency and resolution. Principles of gas-liquid chromatography; instrumentation
for gas chromatography. High performance liquid chromatography - practice
and equipment design. Ion exchange, size-exclusion and affinity chromatography.
Electrophoretic techniques. CHM418Y1
An experimental or theoretical research problem under the supervision of a member of staff. Applications for enrolment should be made to the Department in the preceding Winter Session. CHM421H1
Reaction mechanisms; collision dynamics; theory of the rates of elementary processes; introduction to complex reactions including nonlinear processes. CHM423H1
Applications of time independent and time dependent perturbation theory to atomic and molecular problems; WKB approximation and the classical limit; the interaction of light with matter; elementary atomic scattering theory. CHM426H1
Scope of polymer chemistry. Organic and inorganic polymers. Synthesis and characterization of polymers. Polymers as advanced materials. Polymers in solution: Flory-Huggins theory. Polymers in the solid state: crystalline and amorphous polymers, the effects of the glass transition on polymer properties. CHM427H1
Ensemble theory in statistical mechanics. Applications, including imperfect gases and liquid theories. Introduction to non-equilibrium problems. CHM428Y1
An experimental or theoretical research problem under the supervision of a member of the Physical Chemistry staff. Enrolment in this course may be restricted and must be approved by the Department. Applications for enrolment should be made to the Department in the preceding Winter Session. CHM432H1
Structure, bonding, and reactions of organometallic compounds, with emphasis on basic mechanisms, and industrial processes. Addition, metalation, substitution, elimination, important catalytic cycles, electrophilic, and nucleophilic reactions are considered on a mechanistic basis. Properties of s and p block organometallics. CHM434H1
A comprehensive investigation of synthetic methods for preparing diverse classes of inorganic materials with properties intentionally tailored for a particular use. Begins with a primer on solid-state materials and electronic band description of solids followed by a survey of archetypical solids that have had a dramatic influence on the materials world, some new developments in materials chemistry and a look at perceived future developments in materials research and technology. Strategies for synthesizing many different classes of materials with intentionally designed structures and compositions, textures and morphologies are then explored in detail emphasizing how to control the relations between structure and property of materials and ultimately function and utility. A number of contemporary issues in materials research are critically evaluated to appreciate recent highlights in the field of materials chemistry - an emerging sub-discipline of chemistry. CHM437H1
Essential elements in biology; naturally occurring and medicinal ligands; transport, uptake and control of concentration of metal ions; physical methods of characterization of metal binding sites. Roles of metal ions: as structural and signaling elements in proteins, nucleic acids and DNA-binding complexes and proteins; as Lewis-acid centres in enzymes; as carriers of electrons, atoms and groups in redox proteins and enzymes; as sources of biominerals; as radiopharmaceuticals. CHM438H1
CHM439Y1
An experimental or theoretical research problem under the supervision of a staff member. Applications for enrolment should be made to the Department in the preceding Winter Session. CHM440H1
Overview of classes of molecules currently used in treatment of diseases. Within each therapeutic area, representative drugs on the market are considered and their syntheses discussed. Reactions taught in previous courses and new reactions are used. Students also gain appreciation of the mode of action, discovery and development of drugs in the pharmaceutical industry today. CHM441H1
Structure and stereochemistry determination using modern spectroscopic techniques. The main focus of the course is on NMR spectroscopy (1H and 13C). Other spectroscopy techniques are discussed briefly, including infrared, X-ray and mass spectral methods. The approach taken emphasizes applications of these spectroscopic methods to organic problems. CHM443H1
Methods for the determination of organic reaction mechanisms, both in a kinetic and non-kinetic sense. Topics include reactive intermediates, product identification, structure/reactivity relationships, solvent effects, kinetic isotope effects and acid/base catalysis CHM447H1
Applications of organic chemistry and physical organic chemistry to the study of biologically important processes. Kinetics and mechanisms of enzyme catalysis, chemistry of co-enzymes, stereochemistry of biological reactions, biosynthesis of important biological molecules. Drug and inhibitor design. Catalytic antibodies. CHM449Y1
An experimental research problem under the supervision of a faculty member. Applications for enrolment should be made to the Department in the preceding Winter Session. Projects in the areas of synthetic, physical and bio-organic chemistry are offered. CHM479H1
An in depth examination of biological systems at the molecular level. Several complex, multi-component molecular machines with a central role in life will be examined. For each system studied, the focus will be on understanding the chemical mechanisms that underlie the biological activities, and how these processes fit into a cellular context. Not offered until 2004-2005. |
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