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PCL299Y1 Credit course for supervised participation in faculty research project. See page 45 for details. PCL201H1 A general introduction to pharmacology. Topics include absorption, distribution, biotransformation, elimination, calculation of dosages, variability in drug response and adverse drug reactions. PCL302H1 Topics include biological action of drugs on membranes, enzymes, receptors, neural and hormonal systems, transmission and modulation. PCL362H1 Toxicological problems encountered in animals and humans; biochemical mechanisms and clinical factors of toxicological significance; models of drug-related diseases. PCL376H1 A practically oriented course, focused on experimental design and the analysis of pharmacological and toxicological data. Topics include: principles of experimental design, data analysis and statistical tests appropriate for each type, use of computing statistical packages, analysis of dose-response and time-response curves and analysis of receptor binding assays. PCL376H1 can be taken either as a prerequisite or a Co-requisite to the research project course PCL472Y1/PCL474Y1. PCL470Y1 Concepts of the properties of drugs and chemicals and their interaction with living systems and their constituent parts. Mechanism of action and pharmacological properties of drugs acting on the autonomic and central nervous systems, cardiovascular, renal, respiratory, gastrointestinal, immunological and endocrine systems; endogenous compounds; antimicrobial and anti-inflammatory drugs, chemotherapy and special topics in pharmacology. PCL471Y1 Demonstrations, seminars, and laboratory exercises in selected areas of Pharmacology. Enrollment in the Pharmacology Laboratory course (PCL471Y1) is restricted to students enrolled in the Pharmacology and Double Specialist programs. PCL472Y1 This course affords students an opportunity for hands-on research experience in a laboratory or applied pharmacology setting. Students will work under the supervision of a staff member and will submit a final written report. Enrollment is limited and requires permission from the Department of Pharmacology. It is the student’s responsibility to secure a placement with an approved supervisor before the course begins (a list of potential supervisors can be obtained from the Department of Pharmacology). Students will be registered in the course once their ballot form (obtained from the Department of Pharmacology) is signed by an approved supervisor and approved by the Department of Pharmacology. . PCL473Y1 A survery course examining traditional and contemporary problems in toxicology. The toxicities associated with a variety of toxins and toxicants are examined. General principles and the application of toxicological knowledge are discussed including clinical toxicology, forensic toxicology, and risk assessment. PCL474Y1 This course affords students an opportunity for hands-on research experience in a laboratory or applied toxicology setting. Students will work under the supervision of a staff member and will submit a final written report. Enrollment is limited and requires permission from the Department of Pharmacology. It is the student’s responsibility to secure a placement with an approved supervisor before the course begins (a list of potential supervisors can be obtained from the Department of Pharmacology). Students will be registered in the course once their ballot form (obtained from the Department of Pharmacology) is signed by an approved supervisor and approved by the Department of Pharmacology. . PCL475Y1 Major neuro-psychiatric disease syndromes: clinical pathology and neuronal abnormalities; CNS drugs: theories and mechanisms of action. PCL477H1 Many anticancer drugs and environmental agents exert their cytotoxic effects through DNA damage. This course explores specific pharmacological and toxicological agents that damage DNA and discusses how mammalian cells respond to this DNA damage. PCL481H1 The biochemical principles and molecular mechanisms underlying the toxicity of drugs and foreign agents. The sequence of events at the molecular level leading to impairment of cell function and the factors which determine and affect toxicity. |
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