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Laboratory Medicine and Pathobiology Courses

Key to Course Descriptions.

For Distribution Requirement purposes, all LMP courses are classified as SCIENCE courses.

| Course Winter Timetable |

LMP299Y1
Research Opportunity Program

Credit course for supervised participation in faculty research project. See page 45 for details.


LMP300Y1
Introduction to Pathobiology         52L, 6P

Concepts in pathogenesis; cell injury and death; tissue structure, wound healing; repair and fibrosis. Molecular basis of major organ system pathology. The laboratory examines gross anatomical specimens and introduces histopathology. Enrolment is limited to students specializing in pathobiology who have completed the first and second year requirements of the program.

Exclusion: LMP301H1


LMP301H1
Introduction to the Biochemistry of Human Disease        26L

Introduces concepts and mechanisms of disease processes as they arise from disturbances of normal biochemical and physiological functions. The rational use of the clinical biochemistry laboratory in the diagnosis and management of disease is explained. Not intended for students in the Pathobiology Specialist program.

Exclusion: LMP300Y1
Prerequisite: BCH210H1
Co-requisite: PSL302Y1/JBO302Y1


LMP363H1
Principles of Pathobiology        26L

Pathological changes brought on by foreign compounds; applications of pathology to the detection of toxic carcinogenic actions.
Prerequisite: BIO250Y1, CHM247H1


LMP365H1
Neoplasia        20L, 6P

A general introduction to the cellular and molecular aspects of cancer and its etiology. The laboratory component presents the range of benign and malignant tumor types at the gross and histological levels. Pathophysiology of cancer, invasion and metastases, role of the immune system.
Co-requisite: LMP300Y1 or permission of department


LMP402H1
Inflammation and Infection        26L

Cellular and molecular components of the inflammatory response. Activation of the inflammatory response by viral and microbial pathogens. Tissue pathology resulting from the inflammatory response. Evolution of pathogens to avoid and exploit the response.
Prerequisite: IMM334Y1/(MGY377H1, MGY378H1)


LMP403H1
Immunopathology        26L

The immune system in disease. Responses of the immune system to host invasion, injurious stimuli, and transplantation. Immunopathology of organ-specific diseases including pancreas, gut, liver, heart, kidney, and blood. Intended for students specializing in pathobiology or related programs.
Prerequisite: IMM334Y1


LMP404H1
Bone and Skeletal Disorders        26L

Molecular and cellular architecture of connective tissue in health and in diseases, such as osteoporosis and arthritis. Cellular and endocrine signals necessary for formation and maintenance of the skeleton. Biomechanics and tissue engineering of bone and cartilage. Selected other connective tissue diseases, their genetic variability, and up-to-date treatment strategies.


LMP405Y1
Project in Laboratory Medicine  and Pathobiology      156P

A self-contained research project to be completed under the supervision of a faculty member. The main areas of research are as listed in the description of the Department (above). The student will normally have completed three full years of study, and is expected to devote at least one full day per week to the project. Admission is by arrangement with the Department and with a particular supervisor. A list of potential supervisors is available from the Departmental Office and on our web site.
Prerequisite: BCH210H1/310H1, LMP300Y1/LMP363H1/LMP365H1 and permission of department


LMP406H1
Pathobiology of the Cardiovascular System        26L

Pathobiology of the heart, blood vessels, and lymphatic system. Congenital diseases of the heart, ischemic injury, stroke. Treatments of vascular disease and cardiovascular biomaterials. Major focus on atherosclerosis and hypertension. The emphasis is on the underlying cell biology of these processes.


LMP410H1
Pathobiology of Neurodegenerative Disease       26L

Molecular basis of neurodegenerative diseases of the central and peripheral nervous systems. Relevant neuroanatomy and molecular biology of the CNS. Current research topics in neurodegenerative diseases.


LMP436H1
Microbial Pathogenesis        39L

Molecular mechanism involved in pathogenesis of infectious disease. Topics include recurrent themes in the establishment of infectious disease, such as adherence and spread of pathogenic bacteria as well as evasion of host defences. Emphasis is placed on genetic characterization and expression of virulence determinants and on interactions between bacterial pathogens and their hosts.
Prerequisite: BCH210H1, IMM334Y1/MGY377H1