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Home | Calendar Contents | Registrar's Office Home | Arts & Science Home Cell and Systems Biology CoursesFor Distribution Requirement purposes, all BIO, BOT and ZOO courses, ENV 234Y1, and JMB 170Y1 are classified as SCIENCE courses. BIO 225H1 This course presents biostatistics to students in the life sciences using
biological examples where appropriate. Students will learn to choose and
use statistics that are appropriate to address relevant biological questions
and hypotheses. Lectures and computer labs will be used to cover the following
methods: sampling and experimental design, data exploration, correlation,
regression, ANOVA, Chi-square and non-parametric tests. |
BIO250Y1 An introduction to the structure and function of cells at the molecular level: key cellular macromolecules; transfer of genetic information; cell structure and function; cellular movement and division; modern investigative techniques. Consult web page for the most current information: http://bio250y.chass.utoronto.ca/ BIO260H1 This is a problem based course which discusses classical, molecular, developmental, and population genetics and genomics with emphasis on model organisms for genetic analysis. BIO349H1 Genome organization and evolution, gene expression and regulation, differentiation and development. Consult web pages for details: http://bio349s.chass.utoronto.ca/ BIO351Y1 An introduction to basic and medical virology. Attendance in tutorials is optional. BIO352H1 Use of available programs for analyzing biological data. This is an introductory course with a strong emphasis on hands-on methods meant for Biology and Human Biology/GGB specialists/majors. Some theory is introduced, but the main focus is on using extant bioinformatics tools to analyze data and generate biological hypotheses. 400-Series CoursesNote BIO482Y1, BIO494Y1, BIO495Y1, BIO496Y1,
and ZOO485Y1 are courses that are advanced in level but are broader in scope, emphasizing
the integration of related sub-disciplines, critical thinking and the synthesis
of ideas often crossing disciplinary boundaries. These courses, generally
taken in fourth year, demand active student participation, and typically
involve several faculty. Students can enrol in only one of these. However,
students wishing to take an additional course should contact the Cell and
Systems Biology, and Ecology and Evolutionary Biology Undergraduate Offices. BIO458H1 A seminar course exploring non-Mendelian phenomena in plants, fungi and animals that reveal aspects of genome organization and regulation that may provide insight into genome function and evolution. BIO461H1 Exploration of the relationships between chromosome structure, function and behaviour. This is an upper level genetics course with considerable cell/molecular biology content. Topics include chromatin structure, essential chromosomal elements, control of mitotic and meiotic segregation, chromosome evolution, genomic imprinting. Tutorials emphasize student discussion of recent primary research papers. BIO472H1 Computational analyses of DNA and RNA expression data. Understanding biological databases, sequence alignment, sequence annotation, gene prediction, computational analysis of function, motif analysis, phylogenetic analysis, and microarray analysis. Applied, theoretical and statistical issues will be addressed. BIO473H1 This course surveys the field of Chemical Genomics, focusing on the analysis of biological problems using chemical approaches. Topics covered include chemical genetics, combinatorial chemistry and combinatorial strategies in molecular biology (such as phage display and other selection schemes). Examines both the underlying biological and chemical concepts; however, the focus is primarily biological. BIO482Y1 A class directed seminar analyzing the major problems in developmental biology from cellular, genetic, and molecular perspectives. BOT299Y1 Credit course for supervised participation in faculty research project. See page 45 for details. BOT340H1 Plant developmental genetics at the molecular, cellular and organismal level, generation and use of genomic resourses in plant model organisms. Plant embryo and meristem development, as well as vascular tissue patterning. Genomic approaches applicable in plant biotechnology include the generation of enhancer-trap and activation-tag collections as well as the exploitation of natural genetic variation to improve fibre properties in trees. BOT350H1 Laboratory methods used in plant molecular biology research. Topics include vector construction, plant transformations, PCR, DNA blots, high-throughput screens, genetic mapping, and bioinformatic analyses. BOT351H1 Plants have co-evolved with microbes ever since their first appearance on land, resulting in sophisticated strategies of pathogenicity, symbiosis, commensalisms and mutualism. This course presents an overview of these strategies with examples of bacteria, fungi, oomycetes and viruses that have evolved intimate associations with plants. BOT398H0/399Y0 An instructor-supervised group project in an off-campus setting. See page 45 for details. BOT421H1 Advanced plant metabolism in relation to primary and secondary bisynthetic processes. Developments in metabolism of acetate, mevalonate, aromatic amino acid and compounds of mixed biosynthetic origin. BOT450H1 This course introduces students to proteomics and metabolomics approaches, such as mass spectrometry, structural biology, 2D gel electrophoresis, in understanding the regulation of metabolic pathways in plants. BOT452H1 This course explores the molecular strategies that microbes and plants have evolved to live with each other. The variety of strategies will be summarized with emphasis on the molecular mechanisms of pathogenic and symbiotic relationships. BOT458H1 This course introduces students to major features of gene expression and signal transduction in plants. Topics include strategies for generating transgenic plants and regulating gene expression, as well as the importance of signal transduction in plant growth and survival. How plants sense and respond at the molecular level to environmental stresses such as drought, salinity, cold and disease will be discussed. The application of this basic scientific information in biotechnological strategies for improving agronomic traits will also be addressed.. BOT460Y1/461H1 A research project, requiring the prior consent of a member of the Department to supervise the project. The topic is to be agreed on by the student and supervisor before enrolment in the course; they must also arrange the time, place, and provision of any materials. Written and oral reports are required. Normally open only to fourth-year students with adequate background in Botany. BOT462Y1/463H1 Selected research/lecture topics in plant sciences offered to advanced students. Students completing a second research project may not be supervised by their BOT460Y1/461H1 faculty sponsor. JBS229H1 Continuation of STA220H1, jointly taught by Statistics and Biology faculty, emphasizing methods and case studies relevant to biologists including experimental design and ANOVA, regression models, categorical and non-parametric methods. JMB170Y1 Applications of mathematics to biological problems in physiology, genetics, evolution, growth, population dynamics, cell biology, ecology and behaviour. Mathematical topics include: power functions and regression; exponential and logistic functions; binomial theorem and probability; calculus, including derivatives, max/min, integration, areas, integration by parts, substitution; differential equations, including linear constant coefficient, systems; and chaos. This course is intended for students in the life sciences. JZP326H1 Daily, monthly, annual and other rhythms and methods of measuring them. Behavioural and physiological aspects of biological clocks. The importance of rhythms in experimental design, in research on brain function, in affective disorders, and the adaptive value of rhythms to animals. (Given by the Departments of Psychology and Zoology) JZP428H1 Circadian rhythms with emphasis on non-photic entrainment and phase shifting of rhythms by behaviour (e.g., social interactions, or becoming active). Properties and physiological mechanisms for non-photic effects and comparisons with those for photic effects. Seminars and readings of original papers. Emphasis on basic principles, but possible applications are also discussed. (Given by the Departments of Psychology and Zoology) MGY460H1 See “Molecular Genetics and Molecular Biology” SCI199H1/Y1 Undergraduate seminar that focuses on specific ideas, questions, phenomena or controversies, taught by a regular Faculty member engaged in the discipline. Open only to newly admitted first year students. It may serve as a breadth requirement course; see page 45. ZOO200Y1 Biological issues and concepts. Human interactions with each other, with other species, and with the physical environment. Human biological and cultural evolution (mechanisms, changes in anatomy, behaviour, conceptualization, resource consumption, biotechnology); sexuality (development, theories and controversies in current research); population growth and environmental impact (carrying capacity, water and land use; pollution, resource management); environmental health (biodiversity, food supply, pesticides, ethics and decision-making). ZOO252Y1 The main ideas of physiology and the contribution of experimentation to our understanding of life processes. Uses examples from throughout the animal kingdom, and includes the physiology of nervous, muscular, sensory and endocrine systems, homeostasis and control mechanisms, salt and water balance, respiration, thermoregulation, reproduction and metabolic processes. ZOO325H1 The regulation of physiological processes by hormones and other signalling molecules in chordates. An integrated genes-to-environment approach is used to examine aspects of hormonal evolution, physiological information flow, behaviour and neuroendocrinology, and xenobiotic endocrine disruptors. ZOO327H1 Examines expression, structure and function of the four major classes of ECM macromolecules: collagen, proteoglycans, non-collagenous structural proteins and glycoproteins. In addition to forming elaborate networks that give tissues and organs their unique architectural design and biophysical properties, ECM molecules act as potent regulators of all cellular activities. Emphasis is placed on the morphoregulatory contribution(s) of ECM molecules to normal and pathological development. ZOO328H1 Basic concepts in developmental biology. Early development of invertebrates and vertebrates will be discussed with emphasis on experimental and molecular analysis of developmental mechanisms. Tutorials demonstrate examples of descriptive and experimental embryology and discuss primary literature of selected topics in developmental biology. ZOO329H1 This course begins with a comparison of embryonic development in the major animal taxa. The evolution of developmental mechanisms is then considered with emphasis on the molecular and genetic basis of these mechanisms. Subsequent discussion examines the impact of developmental processes on the evolution of animal diversity. Tutorials feature the study of embryos representing diverse animal taxa. ZOO330H1 A laboratory based course in current research techniques, employing animal model organisms (fruit fly, zebrafish, frog) and experimental methods including basic molecular and cell biology techniques. ZOO331H1 The development of multicellular organisms is dependent on a broad variety of different cell-cell and cell-matrix adhesive mechanisms. The course examines the molecules and mechanisms involved and how they act in concert to regulate distinct developmental and physiological events. Emphasis is placed on the experimental approaches and technology used to study the molecular interactions and dynamics and alter structure-function relationships in cells and organisms. ZOO332H1 Examination of all aspects of the synapse in both the peripheral and central nervous systems of invertebrates and vertebrates. Topics include: synapse formation, synaptic transmission, synaptic plasticity, learning and memory, and neurological disorders. ZOO344H1 The importance of neurohormones and hormones in the regulation of reproduction, growth, metamorphosis and metabolism in arthropods, especially insects and crustaceans, molluscs, and other invertebrates. ZOO 345H1 Covers theories on the biological function of sleep-wake states – why and how animals sleep. Integrates all levels of organization, including molecular biology, homeostasis, bioenergetics, neurophysiology, endocrinology, behaviour and evolution, with comparisons across phyla. ZOO346H1 Integrated control of cardio-respiratory physiology and metabolism in vertebrates. Topics include exercise, diving, sleep and hibernation. ZOO347H1 In-depth survey of unique cellular adaptations of different tissues and organisms to overcome environmental stresses such as hypoxia. Emphasis is placed on cellular strategies, particularly second messenger responses, although systematic and whole organism responses will be investigated. Broad-ranging common strategies among diverse organisms are examined. ZOO357H1 The biology of malaria and other medically important vector-borne parasitic diseases. Topics include history of medical parasitology, parasite development in human and invertebrate hosts, epidemiology, adaptations to intra- and extracellular life and switching between hosts, effects on host physiology, immunity and behaviour, implications for vaccine and vector control and lessons regarding zoonoses and emergent infectious diseases. Laboratories and discussions complement formal lectures. ZOO398H0/399Y0 An instructor-supervised group project in an off-campus setting. See page 45 for details.
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