PCL299Y1 Research Opportunity Program
Credit course for supervised participation in faculty research project. See page 43 for details.
PCL201H1
Introduction to Pharmacology: Pharmacokinetic Principles 39L, 13T
Topics include absorption, distribution, biotransformation, elimination, calculation of dosages, variability in drug response and
adverse drug reactions.
Recommended Co-requisites: BIO250Y1, CHM217H1/CHM220H1, CHM247H1/CHM249H1
PCL302H1
Introduction to Pharmacology:Pharmacodynamic Principles 39L, 13T
Topics include biological action of drugs on membranes, enzymes, receptors, neural and hormonal systems, transmission and
modulation.
Prerequisites: BIO250Y1, CHM217H1/CHM220H1, CHM247H1/CHM249H1, PCL201H1/301H1 and permission of Department
PCL362H1 Introductory Toxicology 26L
Toxicological problems encountered in animals and humans; biochemical mechanisms and clinical factors of toxicological
significance; models of drug-related diseases.
Prerequisites: BCH210H1, BIO250Y1, CHM217H1/CHM220H1, CHM247H1/CHM249H1, PCL201H1 and permission of Department
Recommended Co-requisite: BIO349H1, PCL302H1
PCL376H1
Experimental Design and Data Analysis for Pharmacology
and Toxicology 26L
A practically oriented course, focused on experimental design and the analysis of pharmacological and toxicological data.
Topics include: principles of experimental design, data analysis and statistical tests appropriate for each type, use of computing
statistical packages, analysis of dose-response and time-response curves and analysis of receptor binding assays. PCL
376H1/476H1 is restricted to students enrolled in one of the three specialist programs offered by the Department of
Pharmacology. PCL376H1/PCL476H1 can be taken either as a pre-requisite (PCL376H1) or a Co-requisite (PCL476H1) to the
project course PCL472Y1/PCL474Y1.
Prerequisite: PCL201H1 and permission of Department
Co-requisite: PCL302H1 and permission of Department
Exclusion: PCL476H1
PCL470Y1 Systems Pharmacology 78L
Concepts of the properties of drugs and chemicals and their interaction with living systems and their constituent parts.
Mechanism of action and pharmacological properties of drugs acting on the autonomic and central nervous systems,
cardiovascular, renal, respiratory, gastrointestinal, immunological and endocrine systems; endogenous compounds;
antimicrobial and anti-inflammatory drugs, chemotherapy and special topics in pharmacology.
Prerequisites: BCH210H1, BIO349H1, PCL201H1, PCL302H1, PSL302Y1 and permission of Department
PCL471Y1 Pharmacology Laboratory 104P
Demonstrations, seminars, and laboratory exercises in selected areas of Pharmacology. Enrolment in the Pharmacology
Laboratory course, PCL471Y1, is restricted to students enrolled in the Pharmacology and Double Specialist programs.
Prerequisites: BCH370H1, PSL372H1, PCL201H1, PCL302H1 and permission of Department
Co-requisite: PCL470Y1
PCL472Y1 Project in Pharmacology
A research project course providing intensive practical experience in a laboratory or applied pharmacology setting. Students
will work under the supervision of a staff member and will submit a final written report. Enrollment is restricted to students
enrolled in the Pharmacology and Double Specialist programs offered by the Department of Pharmacology. It requires the prior
consent of an approved supervisor to supervise the project, and departmental approval before enrolment. Student and
supervisor must follow the departmental guidelines for evaluation. It is the student's responsibility to initiate all necessary
preparations before the session starts.
Prerequisites: PCL201H1, PCL302H1, PCL376H1 (see NOTE number 4, below) and permission of Department
Co-requisite: PCL476H1 (see NOTE number 4, below)
Exclusion: PCL474Y1
PCL473Y1 Interdisciplinary Toxicology 52L
Traditional and contemporary problems in toxicology: general aspects, methodology, nature of toxic damage, general biological
problems, poisons, applications and social policies.
Prerequisites: BCH210H1/310H1, BIO349H1, PCL201H1/301H1, PCL302H1, PCL362H1 and permission of Department
PCL474Y1 Project in Toxicology
A research project course providing intensive practical experience in a laboratory or applied pharmacology setting. Students
will work under the supervision of a staff member and will submit a final written report. Enrollment is restricted to students
enrolled in the Toxicology and Double Specialist programs offered by the Department of Pharmacology. It requires the prior
consent of an approved supervisor to supervise the project, and departmental approval before enrolment. Student and
supervisor must follow the departmental guidelines for evaluation. It is the student's responsibility to initiate all necessary
preparations before the session starts.
Prerequisites: PCL201H1, PCL302H1, PCL376H1 (see NOTE number 4, below) and permission of Department
Co-requisite: PCL476H1 (see NOTE number 4, below)
Exclusion: PCL472Y1
PCL475Y1 Neuropsychopharmacology 78L, 26T
Major neuro-psychiatric disease syndromes: clinical pathology and neuronal abnormalities; CNS drugs: theories and
mechanisms of action.
Prerequisite: Enrolment is limited to students with a minimum CGPA of 3.0, and permission of Department.
PCL476H1 Experimental Design and Data Analysis for Pharmacology
and Toxicology 26L
A practically oriented course, focused on experimental design and the analysis of pharmacological and toxicological data.
Topics include: principles of experimental design, data analysis and statistical tests appropriate for each type, use of computing
statistical packages, analysis of dose-response and time-response curves and analysis of receptor binding assays. PCL
376H1/476H1 is restricted to students enrolled in one of the three specialist programs offered by the Department of
Pharmacology. PCL376H1/PCL476H1 can be taken either as a pre-requisite (PCL376H1) or a Co-requisite (PCL476H1) to the
project course PCL472Y1/PCL474Y1.
Prerequisite: PCL201H1, PCL302H1 and permission of Department
Co-requisite: PCL472Y1/PCL474Y1
Exclusion: PCL376H1
PCL481H1
The Molecular and Biochemical Basis of Toxicology 26L
The biochemical principles and molecular mechanisms underlying the toxicity of drugs and foreign agents. The sequence of
events at the molecular level leading to impairment of cell function and the factors which determine and affect toxicity.
Prerequisites: BCH210H1/310H1, BIO349H1, LMP363H1, PCL362H1 and permission of Department
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