SCI199Y1
First Year Seminar 52S
Undergraduate seminar that focuses on specific ideas, questions, phenomena or controversies, taught by a regular Faculty
member deeply engaged in the discipline. Open only to newly admitted first year students. It may serve as a distribution
requirement course; see page 40.
CHM138H1
Introductory Organic Chemistry I 39L, 18P, 12T
An introduction to principles of structure and their relation to reactivity of
organic molecules: molecular structure,
stereochemistry, functional groups, and reactions. Recommended for students in life and health science programs.
NOTE: CHM138H1 and CHM139H1 may be taken in either order, but not both in the same session.
Exclusion: CHM151Y1, CHM242H5, CHMB41H3,
CHMB42H3
Prerequisite: Chemistry SCH4U, Mathematics MCB4U
Co-requisite: MAT135Y1/MAT137Y1/MAT157Y1 recommended,
but may be required pre-requisite in 2nd year Chemistry courses; PHY138Y1/140Y1
recommended
CHM139H1
Chemistry: Physical Principles 39L, 18P, 12T
Structure of matter, gases, liquids and solids; phase equilibria and phase diagrams; colligative properties; chemical equilibria;
electrolyte solutions and electrochemistry; reaction kinetics; introduction to thermodynamics. Recommended for students in life
and health science programs.
NOTE: CHM138H1 and CHM139H1 may be taken in either order, but not both in the same session.
Exclusion: CHM151Y1, CHMA10H3, CHMA11H3
Prerequisite: Chemistry SCH4U, Mathematics MCB4U
Co-requisite: MAT135Y1/MAT137Y1/MAT157Y1 recommended,
but may be required pre-requisite in 2nd year Chemistry courses; PHY138Y1/140Y1
recommended
CHM151Y1
Chemistry: The Molecular Science 78L, 35P, 26T
An introduction to the major areas of modern chemistry, including (1) organic
and biological chemistry, (2) physical chemistry
and chemical physics, (3) inorganic and materials chemistry. The course is intended for students specializing in chemistry or a
related science. The combination of CHM151Y1 and CHM249H1 serves as a full year introductory course in organic chemistry
with laboratory.
Note: Students taking Chemistry and Physics may schedule the labs on the same afternoon of alternate weeks.
Exclusion: (CHM138H1, CHM139H1),
CHM140Y5, CHMA10H3, CHMA11H3
Prerequisite: Chemistry SCH4U, Mathematics MCB4U; Physics SPH4U recommended
Co-requisite: MAT135Y1/MAT137Y1/MAT157Y1; PHY138Y1/PHY140Y1
CHM200Y1
The Role of Chemistry in Modern Society 52L
Human beings are constructed physically of chemicals, live in a sea of chemicals
and are very dependent for their material
quality of life on the modern chemical industry. This course is especially for non-science students who wish to develop a better
understanding of the impact and importance of chemistry in industry, society and the environment. The course should be of
particular interest to students with interests in economics, commerce, management, politics, psychology and teaching. Not
offered in 2005-2006.
Exclusion: Students who have taken one or more university-level courses
in chemistry require permission of the instructor.
Prerequisite: completion of 5 full courses at the university level
CHM217H1
Introduction to Analytical Chemistry 26L, 52P,
13T
Introduction to the science of chemical measurement, from sampling through analysis
to the interpretation of results. Learn
how water, food products, pharmaceuticals, and dietary supplements are analysed for content, quality, and potential
contaminants. Also learn how to handle and interpret experimental measurements, compare results and procedures, and
calibrate analytical instrumentation. Through closely integrated lectures, laboratories, and tutorials, this highly practical course
will introduce you to a variety of analytical techniques including volumetric methods, potentiometry, uv/visible and infrared
spectrophotometry, flame atomic absorption spectrometry, and chromatography.
Prerequisite: (CHM138H1, CHM139H1)/CHM151Y1 with a minimum grade of 65%, or permission from the department
CHM220H1
Physical Chemistry for Life Sciences 39L, 13T
Introduction to thermodynamics; phase equilibrium, chemical equilibrium, electrochemistry;
introduction to quantum mechanics
and spectroscopy.
Exclusion: CHM225Y1, 221H5
Prerequisite: (CHM138H1, CHM139H1)/CHM151Y1; MAT135Y1/MAT137Y1/MAT157Y1
Recommended Co-requisite: MAT235Y1/MAT237Y1
CHM221H1
Physical Chemistry: The Molecular Viewpoint 26L,
13T
Intended as a continuation of CHM220H1 for students wishing to take some additional material in Physical Chemistry. The
course covers topics in quantum mechanics and spectroscopy as well as an introduction to reaction kinetics.
Exclusion: CHM225Y1, 221H5
Prerequisite: CHM220H1 with a minimum grade of 65%, or permission from the department
Recommended Co-requisite: MAT235Y1/MAT237Y1
CHM225Y1
Introduction to Physical Chemistry 52L, 26T
Directed to students in the Chemistry major and specialist programs. Topics: introductory thermodynamics, first and second
law and applications; chemical equilibrium; electrochemistry, surface chemistry; chemical kinetics; introductory quantum
mechanics; spectroscopy, and molecular photophysics.
Exclusion: CHM220H1, CHM221H1, 221H5
Prerequisite: [(CHM138H1, CHM139H1)/CHM151Y1 with
a minimum grade of 65%, or permission from the department], MAT135Y1/MAT137Y1/MAT157Y1,
PHY138Y1/PHY140Y1
Recommended Co-requisite: MAT235Y1/MAT237Y1
ENV235Y1
Physics and Chemistry of Planet Earth 52L, 26T
(see Division of the Environment)
This course considers the fundamental chemical and physical processes of the Earth's natural environment. The first semester
of the course focuses primarily on the atmosphere: its evolution, structure, composition and dynamical character. Particular
emphasis is given to a discussion of global climate and the underlying physical, chemical and biogeochemical factors that drive
climate change. Within this context, stratospheric ozone depletion, ocean chemistry, urban air pollution, acid rain and water
quality are also discussed. The second semester focuses on the solid Earth: its formulation and evolution, internal dynamics,
mantle-core differentiation, volcanism, tectonics and paleoclimate/ice ages. Throughout the course, the operation of the Earth
as a coupled physico-chemical system over a range of timescales is emphasized.
Prerequisite: (CHM138H1, CHM139H1)/CHM151Y1, MAT135Y1/MAT137Y1/JMB170Y1, PHY138Y1/PHY140Y1
CHM238Y1
Introduction to Inorganic Chemistry 52L, 52P
The first part (with CHM338H1) of a two-year sequence in Inorganic Chemistry, designed to illustrate and systematize the rich
variety of structures, physical properties and reactions of compounds of the elements across and down the Periodic Table.
Introduction to structure, symmetry and bonding of molecules and lattices; acid-base and redox reactions; d-metal complexes;
systematic chemistry of metals and elements of the s and p blocks; inorganic materials and solid state chemistry with
applications in advanced technologies.
Prerequisite: CHM151Y1/(CHM138H1, CHM139H1) with a minimum grade of 65%, or permission from the department
CHM247H1
Introductory Organic Chemistry II 39L, 22P, 12T
Reactions of organic compounds. Principles of mechanism, synthesis, and spectroscopy, continuing from CHM138H1. Tutorial
(12T) is optional.
Exclusion: CHM249H1, CHM242H5, CHM243H5, CHMB41H3, CHMB42H3
Prerequisite: (CHM138H1, CHM139H1)/CHM151Y1
CHM249H1
Organic Chemistry 39L, 48P
An in-depth survey of organic molecules and principles of their reactions. Emphasis is on understanding of the basics with
respect to structure and bonding, and application of reactions to the synthesis of medicinally and industrially important
compounds. This course continues from CHM151Y1 or CHM138H1 and is designed for students in the Chemistry specialist
and major programs.
Exclusion: CHM247H1, CHM242H5, CHM243H5, CHMB41H3, CHMB42H3
Prerequisite: CHM151Y1/(CHM138H1, CHM139H1) with a minimum grade of 65%, or permission from the department
CHM299Y1
Research Opportunity Program
Credit course for supervised participation in faculty research project. See page 43 for details.
CHM310H1
Environmental Chemistry 26L
Major chemical pollutants and their sources, the environmental reactions they undergo, and how they become distributed
throughout the environment. Focus is on the principal routes of chemical and biological degradation of toxicants; oxidation,
photodegradation, hydrolysis, reduction, biotic metabolism, and microbial degradation. The principal physical processes by
which chemicals move, concentrate, and dissipate.
Prerequisite: CHM247H1/CHM249H1
CHM317H1
Introduction to Instrumental Methods of Analysis 26L, 52P
Scope of instrumental analytical chemistry; Fourier transform IR absorption spectroscopy; molecular luminescence; emission
spectroscopy; mass spectroscopy, electrochemical techniques; sensors; gas and high performance liquid chromatography;
instrument design principles and applications in industry and the environment.
Prerequisite: CHM217H1 with a minimum grade of 65%, or permission from the department
Recommended preparation: (CHM220H1, CHM221H1)/CHM225Y1
CHM325H1
Materials Chemistry 26L
Fashioned to illustrate how inorganic and polymer materials chemistry can be rationally used to synthesize superconductors,
metals, semiconductors, ceramics, elastomers, thermoplastics, thermosets and polymer liquid crystals, with properties that can
be tailored for applications in a range of advanced technologies. Coverage is fairly broad and is organized to crosscut many
aspects of the field.
Prerequisite: CHM220H1/CHM225Y1, CHM238Y1, CHM247H1/CHM249H1
CHM326H1
Introductory Quantum Mechanics and Spectroscopy 26L
This course introduces the postulates of quantum mechanics to develop the fundamental framework of quantum theory. A
number of exactly soluble problems are treated in detail as examples. Perturbation theory is introduced in the context of
understanding many body problems. Various applications to molecular spectroscopy and dynamics are covered in detail.
Prerequisite: CHM225Y1/(CHM220H1, CHM221H1), MAT235Y1/MAT237Y1
CHM327H1
Experimental Physical Chemistry 13L, 52P
Students are exposed to experiments to help them experience modern physical chemistry. Labs designed to illustrate physical
chemistry principles and practical techniques as well as their real world state of the art applications. The course also involves
some lecture material to broaden the laboratory experience.
Prerequisite: CHM225Y1/(CHM220H1, CHM221H1) with a minimum grade of 65%, or permission from the department
Recommended Co-requisites: CHM326H1 or CHM328H1
CHM328H1
Modern Physical Chemistry 26L
This course explores the microscopic description of macroscopic phenomena in chemistry. Statistical mechanics is introduced
as the bridge between the microscopic and macroscopic views, and applied to a variety of chemical problems including
reaction dynamics. More advanced topics in thermodynamics are introduced and discussed as required.
Prerequisite: CHM225Y1/(CHM220H1, CHM221H1), MAT235Y1/MAT237Y1
CHM338H1
Intermediate Inorganic Chemistry 26L, 52P
Further study of the structures, physical properties and reactions of compounds of the main group elements and the transition
metals. Introductions to spectroscopy and structural analysis, reaction mechanisms, d- and f- block organometallic compounds,
catalysis, structures of solids and bioinorganic chemistry. The weekly laboratory demonstrates aspects of transition metal
chemistry.
Prerequisite: CHM238Y1 with a minimum grade of 65%, or permission from the department
Recommended Preparation: CHM217H1, CHM247H1/CHM249H1
CHM345H1
Modern Organic Synthesis 26L
An overview of the preparation of various classes of organic compounds. Strategies and tactics of synthetic organic chemistry
using examples from natural products and pharmaceuticals. C-C bond formation, functional group reactivity, structure,
stereochemistry and selectivity. (This course is not allowed for students in any of the Chemistry specialist and major programs;
they should consider CHM346H1 instead.)
Exclusion: CHM346H1
Prerequisite: CHM247H1/CHM249H1 with a minimum grade of 65%, or permission from the department
CHM346H1
Modern Organic Synthesis 26L, 52P
An overview of the preparation of various classes of organic compounds. Strategies and tactics of synthetic organic chemistry
using examples from natural products and pharmaceuticals. C-C bond formation, functional group reactivity, structure,
stereochemistry and selectivity. (Students who are not in one of the Chemistry specialist or major programs should consider
taking CHM345H1 instead of this course.)
Exclusion: CHM345H1
Prerequisite: A minimum grade of 65% in CHM249H1/CHM247H1
CHM347H1
Organic Chemistry of Biological Compounds 26L, 13T
An organic chemical approach to the structure and reactions of major classes of biological molecules: carbohydrates, amino
acids, peptides and proteins, phosphates, lipids, heterocycles, vitamins, nucleotides and polynucleotides. This is achieved
through studies of advanced stereochemistry, chemical modification, reactions and synthesis. In addition to lectures and
reading from texts, there will be independent written assignments on more advanced topics.
Prerequisite: CHM247H1/CHM249H1
CHM348H1
Organic Reaction Mechanisms 26L, 26P
Analysis of structure and reactions of organic molecules in terms of physical principles. Mechanisms of important classes of
organic reactions.
Prerequisite: CHM247H1/CHM249H1 with a minimum grade of 65%, or permission from the department
CHM379H1
Biomolecular Chemistry 26L, 48P
This course provides an opportunity to learn core techniques in biological chemistry in a small group laboratory setting.
Lectures will discuss the theory behind the techniques and highlight how they are used in current biological chemistry research
and practice.
Exclusion: BCH370H1, BCH371H1
Prerequisite: (CHM247H1/CHM249H1, CHM347H1 with a minimum grade of 65%, or permission from the department), BCH210H1
CHM398H0/399Y0
Independent Experiential Study Project
An instructor-supervised group project in an off-campus setting. See page 43 for details.
CHM409Y1
Introduction to Research in Environmental Chemistry 260P
An experimental or theoretical research problem under the supervision of a member of staff. Applications for enrolment should
be made to the Department in the preceding Winter Session.
Exclusion: CHM418Y1/CHM428Y1/CHM439Y1/CHM449Y1
Prerequisite: Permission of Department
Recommended preparation: CHM314Y1/CHM317H1
CHM410H1
Analytical Environmental Chemistry 26L, 32P
An analytical theory, instrumental, and methodology course focused on the measurement of pollutants in soil, water, air, and
biological tissues and the determination of physical/chemical properties including vapour pressure, degradation rates,
partitioning.
Lab experiments involve application of theory.
Prerequisite: CHM310H1
Recommended preparation: CHM314Y1/CHM317H1
CHM414H1
Developing Techniques in Analytical Chemistry 26L
Current research in analytical chemistry with emphasis on rapidly emerging techniques. Course topics chosen from biosensor
technology, transducer theory and operation, device design and fabrication, surface modification and methods of surface
analysis, flow injection analysis and chemometrics.
Recommended preparation: CHM217H1/314Y1/CHM317H1
CHM415H1
Atmospheric Chemistry 26L
This course considers the chemistry occurring in the Earth's atmosphere, with emphasis on developing molecular-level
understanding of the photochemistry, free-radical kinetics, and heterogeneous chemistry that occurs. Topics include
stratospheric ozone depletion, trace gas oxidation, urban air pollution, acid rain, and the connections between aerosols and
climate.
Prerequisite: CHM220H1/CHM225Y1/CHM310H1
Recommended preparation: MAT135Y1/MAT137Y1; PHY138Y1/PHY140Y1
CHM416H1
Separation Science 26L
Principles of separation in analytical chemistry. Fractionation processes and solvent extractions; theory of chromatography,
retention time, column efficiency and resolution. Principles of gas-liquid chromatography; instrumentation for gas
chromatography. High performance liquid chromatography - practice and equipment design. Ion exchange, size-exclusion and
affinity chromatography. Electrophoretic techniques.
Prerequisite: CHM314Y1/CHM317H1
CHM417H1
Instrumentation for Chemists 26L
Basic understanding of components used in machines conventionally applied to chemical analysis and research. Electronic
circuits and measurement; optical components; analog-digital conversion; lock-in amplifiers and frequency counters; interfaces
for data acquisition and LabView; signal control.
Prerequisite: CHM317H1
CHM418Y1
Introduction to Research in Analytical Chemistry 260P
An experimental or theoretical research problem under the supervision of a member of staff. Applications for enrolment should
be made to the Department in the preceding Winter Session.
Exclusion: CHM409Y1/CHM428Y1/CHM439Y1/CHM449Y1
Prerequisite: Permission of Department
Recommended preparation: CHM314Y1/CHM317H1
CHM421H1
Chemical Kinetics & Dynamics 26L
Reaction mechanisms; collision dynamics; theory of the rates of elementary processes; introduction to complex reactions
including nonlinear processes.
Prerequisite: (CHM326H1, CHM328H1)
CHM423H1
Applications of Quantum Mechanics 26L
Applications of time independent and time dependent perturbation theory to atomic
and molecular problems; WKB
approximation and the classical limit; the interaction of light with matter; elementary atomic scattering theory.
Prerequisite: CHM326H1
Recommended preparation: MAT223H1
CHM426H1
Polymer Chemistry 26L
Scope of polymer chemistry. Classification of polymers. Synthesis and characterization. Polymers in solution. Thermodynamics
of polymer solutions and blends, Flory-Huggins theory. Polymers in the solid state. Crystalline and amorphous polymers. Glass
transition and melting temperature. Mechanical properties. Polymers as advanced materials.
Prerequisite: CHM325H1; two of CHM328H1, CHM338H1, CHM348H1/permission of the instructor
CHM427H1
Statistical Mechanics 26L
Ensemble theory in statistical mechanics. Applications, including imperfect gases and liquid theories. Introduction to non-
equilibrium problems.
Prerequisite: (CHM326H1, CHM328H1)
CHM428Y1
Introduction to Research in Physical Chemistry 260P
An experimental or theoretical research problem under the supervision of a member
of the Physical Chemistry staff. Enrolment
in this course may be restricted and must be approved by the Department. Applications for enrolment should be made to the
Department in the preceding Winter Session.
Exclusion: CHM409Y1/CHM418Y1/CHM439Y1/CHM449Y1
Prerequisite: CHM326H1/CHM328H1, CHM327H1, permission of Department
CHM432H1
Organometallic Chemistry 26L
Structure, bonding, and reactions of organometallic compounds, with emphasis on basic mechanisms, and industrial
processes. Addition, metalation, substitution, elimination, important catalytic cycles, electrophilic, and nucleophilic reactions are
considered on a mechanistic basis. Properties of s and p block organometallics.
Prerequisite: CHM338H1
Recommended preparation: CHM348H1
CHM434H1
Solid State Materials Chemistry 26L
A comprehensive investigation of synthetic methods for preparing diverse classes of inorganic materials with properties
intentionally tailored for a particular use. Begins with a primer on solid-state materials and electronic band description of solids
followed by a survey of archetypical solids that have had a dramatic influence on the materials world, some new developments
in materials chemistry and a look at perceived future developments in materials research and technology. Strategies for
synthesizing many different classes of materials with intentionally designed structures and compositions, textures and
morphologies are then explored in detail emphasizing how to control the relations between structure and property of materials
and ultimately function and utility. A number of contemporary issues in materials research are critically evaluated to appreciate
recent highlights in the field of materials chemistry - an emerging sub-discipline of chemistry.
Prerequisite: CHM325H1, CHM338H1
CHM437H1
Bio-Inorganic Chemistry 26L
Essential elements in biology; naturally occurring and medicinal ligands; transport, uptake and control of concentration of metal
ions; physical methods of characterization of metal binding sites. Roles of metal ions: as structural and signaling elements in
proteins, nucleic acids and DNA-binding complexes and proteins; as Lewis-acid centres in enzymes; as carriers of electrons,
atoms and groups in redox proteins and enzymes; as sources of biominerals; as radiopharmaceuticals.
Prerequisite: CHM238Y1
Recommended preparation: CHM338H1, CHM347H1/CHM379H1
CHM438H1
Advanced Inorganic and Materials Chemistry Laboratory 130P
The 4-week format of the lab bridges the gap between typical undergraduate labs
and the realities of academic and industrial
research and provides an exceptional educational opportunity for students intending to do honours research projects or
considering going on in graduate studies. The lab is open throughout the day for the first four weeks of the fall term and
instructional staff are available during this time to provide guidance on an individual basis.
Applications for enrolment should be made to the Department in the preceding Winter Session.
Prerequisite:
Inorganic Specialist students: CHM238Y1, CHM338H1 and permission of Department
Materials Science Specialist students: CHM238Y1, CHM325H1 and permission of Department
CHM439Y1
Introduction to Research in Inorganic Chemistry 260P
An experimental or theoretical research problem under the supervision of a staff
member. Applications for enrolment should be
made to the Department in the preceding Winter Session.
Exclusion: CHM409Y1/CHM418Y1/CHM428Y1/CHM449Y1
Prerequisite: Permission of Department
Co-requisite: CHM438H1
CHM440H1
The Synthesis of Modern Pharmaceutical Agents 26L
Overview of classes of molecules currently used in treatment of diseases. Within
each therapeutic area, representative drugs
on the market are considered and their syntheses discussed. Reactions taught in previous courses and new reactions are
used. Students also gain appreciation of the mode of action, discovery and development of drugs in the pharmaceutical
industry today.
Prerequisite: CHM345H1/CHM346H1
CHM441H1
Spectroscopic Analysis in Organic Chemistry 26L, 6P
Structure and stereochemistry determination using modern spectroscopic techniques.
Several techniques are discussed but
particular emphasis is given to NMR (1H and 13C NMR) and mass spectrometry. The approach taken emphasizes applications
of these spectroscopic methods to organic problems. Students are trained to run their own spectra (IR, UV, NMR, GC-MS).
Prerequisite: CHM345H1/CHM346H1/CHM348H1
CHM443H1
Physical Organic Chemistry 26L
Methods for the determination of organic reaction mechanisms, both in a kinetic and non-kinetic sense. Topics include reactive
intermediates, product identification, structure/reactivity relationships, solvent effects, kinetic isotope effects and acid/base
catalysis
Prerequisite: CHM220H1/CHM225Y1, CHM348H1
CHM447H1
Bio-organic Chemistry 26L
Applications of organic chemistry and physical organic chemistry to the study of biologically important processes. Topics
include kinetics and mechanisms of enzyme catalysis, chemistry of co-enzymes, drug and inhibitor design, catalytic
antibodies.
Prerequisite: BCH210H1/BCH242Y1/310H1/321Y1/ CHM379H1/CHM347H1
Recommended preparation: CHM348H1
CHM449Y1
Introduction to Research in Organic Chemistry 260P
An experimental research problem under the supervision of a faculty member. Applications
for enrolment should be made to
the Department in the preceding Winter Session. Projects in the areas of synthetic, physical and bio-organic chemistry are
offered.
Exclusion: CHM409Y1/CHM418Y1/CHM428Y1/CHM439Y1
Prerequisite: Permission of Department
Recommended preparation: CHM346H1/CHM348H1/CHM379H1
CHM479H1
Biological Chemistry 26L
An in depth examination of biological systems at the molecular level. Several complex, multi-component molecular machines
with a central role in life will be examined. For each system studied, the focus will be on understanding the chemical
mechanisms that underlie the biological activities, and how these processes fit into a cellular context.
Prerequisite: CHM447H1, BCH210H1/BCH242Y1
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