| Course Winter Timetable |

PCL299Y1
Research Opportunity Program

Credit course for supervised participation in faculty research project. See page 40 for details.

PCL201H1
Introduction to Pharmacology: Pharmacokinetic Principles 39L, 13T

Topics include absorption, distribution, biotransformation, elimination, calculation of dosages, variability in drug response and adverse drug reactions.
Exclusion: PCL301H1
Recommended co-requisites: BIO250Y1, CHM217H1/CHM220H1, CHM247H1/CHM249H1

PCL302H1
Introduction to Pharmacology: Pharmacodynamic Principles 39L, 13T

Topics include biological action of drugs on membranes, enzymes, receptors, neural and hormonal systems, transmission and modulation.
Prerequisites: BIO250Y1, CHM217H1/CHM220H1, CHM247H1/CHM249H1, PCL201H1/301H1 and permission of Department

PCL362H1
Introductory Toxicology 26L

Toxicological problems encountered in animals and humans; biochemical mechanisms and clinical factors of toxicological significance; models of drug-related diseases.
Prerequisites: BCH210H1, BIO250Y1, CHM217H1/CHM220H1, CHM247H1/CHM249H1, PCL201H1 and permission of the Department
Recommended Co-requisite: BIO349H1, PCL302H1

PCL470Y1
Systems Pharmacology 78L

Concepts of the properties of drugs and chemicals and the mechanisms of their interaction with living systems and their constituent parts. Pharmacology of nervous, cardiovascular, renal, respiratory, gastrointestinal and endocrine systems; endogenous compounds; chemotherapy.
Prerequisites: BCH210H1, BIO349H1, PCL201H1, PCL302H1, PSL302Y1 and permission of Department

PCL471Y1
Pharmacology Laboratory 104P

Demonstrations, seminars, and laboratory exercises in selected areas of Pharmacology.
Prerequisites: BCH370H1, PSL372H1, PCL201H1, PCL302H1 and permission of Department (see NOTE below)
Co-requisite: PCL470Y1

PCL472Y1
Project in Pharmacology

A research project course providing intensive practical experience in a laboratory or applied pharmacology setting. Students will work under the supervision of a staff member and will submit a final written report.
Prerequisites: PCL201H1, PCL302H1 and permission of Department

PCL473Y1
Interdisciplinary Toxicology 52L

Traditional and contemporary problems in toxicology: general aspects, methodology, nature of toxic damage, general biological problems, poisons, applications and social policies.
Prerequisites: BCH210H1/310H1, BIO349H1, PCL201H1/301H1, PCL302H1, PCL362H1 and permission of Department

PCL474Y1
Project in Toxicology

A research project course providing intensive practical experience in a laboratory or applied toxicology setting. Students will work under the supervision of a staff member and will submit a final written report.
Prerequisites: PCL201H1, PCL302H1 and permission of Department

PCL475Y1
Neuropsychopharmacology 78L, 26T

Major neuro-psychiatric disease syndromes: clinical pathology and neuronal abnormalities; CNS drugs: theories and mechanisms of action. (Not offered in 2003-2004).
Prerequisite: Permission of Department (see NOTE below)

PCL476H1
Experimental Design and Data Analysis for Pharmacology and Toxicology 26L

A practically oriented course, focused on experimental design and the analysis of pharmacological and toxicological data. Topics include: principles of experimental design, data analysis and statistical tests appropriate for each type, use of computing statistical packages, analysis of dose-response and time-response curves and analysis of receptor binding assays. (First offered in 2004-2005)
Prerequisite: PCL201H1/301H1, PCL302H1 and permission of Department
Co-requisite: PCL472Y1/PCL474Y1 (see Note below)

PCL481H1
The Molecular and Biochemical 26L

Basis of Toxicology
The biochemical principles and molecular mechanisms underlying the toxicity of drugs and foreign agents. The sequence of events at the molecular level leading to impairment of cell function and the factors which determine and affect toxicity.
Prerequisites: BCH210H1/310H1, BIO349H1, LMP363H1, PCL362H1 and permission of Department