| Course Winter Timetable |

PCL299Y1
Research Opportunity Program

Credit course for supervised participation in faculty research project. See page 44 for details.

PCL201H1
Introduction to Pharmacology: Pharmacokinetic Principles 39L, 13T

Topics include absorption, distribution, biotransformation, elimination, calculation of dosages, variability in drug response and
adverse drug reactions.
Exclusion: PCL 301H1
Recommended co-requisites:
BIO 250Y1, CHM 248Y1 or 217H/220H, 247H

PCL302H1
Introduction to Pharmacology: Pharmacodynamic Principles 39L, 13T

Topics include biological action of drugs on membranes, enzymes, receptors, neural and hormonal systems, transmission and
modulation.
Prerequisites: BIO 250Y1, CHM 217H1/220H1, 240Y1/247H1/248Y1, PCL 201H1/301H1 and permission of Department

PCL362H1
Introductory Toxicology 26L

Toxicological problems encountered in animals and humans; biochemical mechanisms and clinical factors of toxicological
significance; models of drug-related diseases.
Prerequisites: BCH 210H1/310H1, BIO 250Y1, CHM 217H1/220H1, 240Y1/247H1/248Y1, PCL 201H1 and permission of the Department

Recommended Co-requisite: JLM 349H1, PCL 302H1

PCL470Y1
Systems Pharmacology 78L

Concepts of the properties of drugs and chemicals and the mechanisms of their interaction with living systems and their constituent
parts. Pharmacology of nervous, cardiovascular, renal, respiratory, gastrointestinal and endocrine systems; endogenous compounds;
chemotherapy.
Prerequisites: BCH 210H1/310H1, JLM 349H1, PCL 201H1/301H1, 302H1, PSL 302Y1 and permission of Department

PCL471Y1
Pharmacology Laboratory 104P

Demonstrations, seminars, and laboratory exercises in selected areas of Pharmacology.
Prerequisites: BCH 370H1, PSL 372H1, PCL 201H1/301H1, 302H1 and permission of Department (see NOTE below)

Co-requisite: PCL 470Y1

PCL472Y1
Project in Pharmacology

Research project with reading assignments and a final written report by special arrangement with professors in the Department of
Pharmacology, and other associated Departments.
Prerequisite: Permission of Department (see NOTE below)

PCL473Y1
Interdisciplinary Toxicology 52L

Traditional and contemporary problems in toxicology: general aspects, methodology, nature of toxic damage, general biological
problems, poisons, applications and social policies.
Prerequisites: BCH 210H1/310H1, JLM 349H1, PCL 201H1/301H1, 302H1, 362H1 and permission of Department

PCL474Y1
Project in Toxicology

Research project with reading assignments and a final written report by special arrangement with professors in the Departments of
Pathology, Pharmacology, Pharmacy and other associated Departments.
Prerequisite: Permission of Department (see NOTE below)

PCL475Y1
Neuropsychopharmacology 78L, 26T

Major neuro-psychiatric disease syndromes: clinical pathology and neuronal abnormalities; CNS drugs: theories and mechanisms of
action.
Prerequisite: Permission of Department (see NOTE below)

PCL476H1
Experimental Design and Data Analysis for Pharmacology and Toxicology 26L

A practically oriented course, focused on experimental design and the analysis of pharmacological and toxicological data. Topics
include: principles of experimental design, data analysis and statistical tests appropriate for each type, use of computing statistical
packages, analysis of dose-response and time-response curves and analysis of receptor binding assays.
Prerequisite: PCL 201H1/301H1, 302H1 and permission of Department
Co-requisite: PCL 472Y1/474Y1 and permission of Department (see NOTE below)

PCL481H1
The Molecular and Biochemical Basis of Toxicology 26L

The biochemical principles and molecular mechanisms underlying the toxicity of drugs and foreign agents. The sequence of events at
the molecular level leading to impairment of cell function and the factors which determine and affect toxicity.
Prerequisites: BCH 210H1/310H1, JLM 349H1, LMP 363H1, PCL 362H1 and permission of Department


NOTES
1. Enrolment in the Pharmacology Laboratory course, PCL 471Y1, is limited.


2. The research project courses, PCL 472Y1 and PCL 474Y1, require the prior consent of an approved supervisor to
supervise the project, and departmental approval before enrolment. Student and supervisor must follow the
departmental guidelines for evaluation. It is the student's responsibility to initiate all necessary preparations
before the session starts.


3. Enrolment in PCL475Y1 is limited to students with a minimum CGPA of 3.0.


4. PCL476H1 is restricted to students enrolled in the specialist programs offered by the Department of
Pharmacology.