Faculty of Arts & Science
2016-2017 Calendar

Physiology

Faculty


Professors Emeriti
U. Ackermann, PhD
H.L. Atwood, PhD, DSc, FRSC
P. Backx, PhD
J.R.G. Challis, PhD, DSc, FIBiol, FRCOG, FRSC
M.P. Charlton, PhD
J. Dostrovsky, PhD
P.E. Hallett, MD
A.A. Horner, PhD
D.R. McLachlan, MD, FRCP(C)
K. Norwich, MD, PhD
M. Percy, PhD
M. Radomski, PhD
H. Sonnenberg, PhD
A.M-F. Sun, PhD
M. Vranic, MD, DSc, FRCP(C), FRSC
J.M. Wojtowicz, PhD

Professor and Chair of the Department
G.L. Collingridge, FRS, FMedSci, FSB, FBPhS

Professors
G.H. Anderson, PhD
D. Bagli, MDCM, FRCSC, FAAP, FACS
C.E. Bear, PhD
J. Belik, MD, FRCP(C)
D. Belsham, PhD
A. Bocking, MD, FRCS(C)
S.-S. Bolz, MD, PhD
R. Boonstra, PhD
T.J. Brown, PhD
P.L. Brubaker, PhD
A. Buchan, PhD
I. Caniggia, MD, PhD
P.L. Carlen, MD, FRCP(C)
R.F. Casper, MD, FRCS(C)
J. Eubanks, PhD
I.G. Fantus, MD, FRCP(C)
Z.P. Feng, MD, PhD
J. Fisher, MD, FRCP(C)
H.Y. Gaisano, MD
A. Giacca, MD
G. Hare, MD, PhD, FRCP(C)
R.V. Harrison, BSc, PhD
R. Horner, PhD
M. Husain, MD, FRCP(C)
W. Hutchison, PhD
Z. Jia, PhD
T. Jin, MD, PhD
N. Jones, MD, PhD, FRCP(C)
B. Kavanagh, BSc, FRCP(C)
J. Kingdom, MD, FRCSC, MRCP, FRCOG
A. Klip, PhD
W.M. Kuebler, MD
J. Laffey, MD, MA, FCARCSI
T.K.T. Lam, PhD
R. Levitan, MD, FRCPC, MSc
G. Lewis, MBBCH, FRCP(C)
F. Liu, PhD
M. Liu, MD, MSc
S.J. Lye, BSc, PhD
R.L. Macdonald, MD, PhD, FRCS(C)
S. G. Matthews, PhD
C.D. Mazer, MD, FRCP(C)
A. McGahan, PhD
P. McNamara, MRCP
F. Miller, PhD, FRSC
H. Ni, MD, PhD
B. Orser, MD, PhD
M. Palmert, MD, PhD
Z. Pausova, MD
J. Peever, PhD
P.S. Pennefather, PhD
M. Post, DVM, PhD
N.D. Rosenblum, MD
M.W. Salter, MD, PhD, FRSC
L.C. Schlichter, PhD
J.W. Scholey, MD, FRCP(C)
Z. Seltzer, DMD
B.J. Sessle, MDS, PhD
F. Skinner, MA, Sc, PhD
E.F. Stanley, PhD
S. Thomas, PhD
W.S. Trimble, PhD
D. Tweed, PhD
M. Tymianski, MD, PhD, FRCS(C)
L.-Y. Wang, PhD
M. Wheeler, PhD
C. Wittnich, DVM, MSc
H. Zhang, MD, PhD
M. Zhen, PhD
M. Zhuo, PhD

Associate Professors
V. S. Chauhan, MD, FRCPC
D. Cherney, MD, PhD, FRCPC
N. Ferguson, MD, FRCPC
P. Frankland, PhD
A. Gramolini, PhD
S. Heximer, PhD
R. Jankov, PhD, FRACP, MB, BS
S. Josselyn, PhD
A. Jurisicova, PhD
E.K. Lambe, PhD
C. Librach, MD, FRCS(C)
J. Min, PhD
P.P. Monnier, PhD, MBA
H. Mount, PhD
D. Ng, PhD, MD, FRCP(C)
S. Prescott, MD, PhD
I. Rogers, PhD
S. Sugita, MA, PhD
H.S. Sun, MD, PhD.
N. Sweezey, MD
V. Watt, PhD

Assistant Professors
B. Cox, PhD
P. McGowan, PhD
C. Nostro, PhD
C. O'Brien, MD, PhD
A. Ramsey, PhD
J.V. Rocheleau, PhD
P. Subbarao, MD
A. Velumian, PhD
X.-Y. Wen, MD, PhD

Associate Professors, Teaching Stream
M. French, PhD
N. Kee, PhD
C. Perumalla, MSc, DPhil

Introduction

Physiology is the study of living matter in action. It integrates physical and life science disciplines in order to understand body functions and the origins of disease. Beyond the study of control mechanisms, compensations, and cooperation among body molecules, cells, tissues and organs, the interaction between the body's external and internal environments is a key theme in Physiology. Most importantly, Physiology unifies the life sciences from molecule to organism, providing the link from genomics and molecular signaling pathways to behaviour and disease. Emerging fields for physiologists are the analysis of the functional implications of genomic sequence variation, developmental factors leading to chronic illness, and novel approaches for regenerative medicine.

Biological function -- of molecules, cells, and organs -- is at the heart of Physiology, and this knowledge is fundamental to the life sciences in general. Accordingly, Physiology provides an excellent and often necessary background for subsequent training in Medicine, Dentistry, Pharmacy, Nursing, Physical or Occupational Therapy, and other health-related professions. It is also excellent preparation for graduate work in Physiology and related areas; or for the teaching of Biological Science in secondary schools. Physiologists are needed in hospitals and departments of medicine as teachers and research personnel. Other outlets would be in agriculture and veterinary medicine, in military research establishments and in life science-based industry. The development of air and space travel, the exploration of the continental shelf, the development of Northern regions, and increased emphasis on exercise and fitness, all provide business and research opportunities for the person trained in Physiology.

Physiology at the research level covers a variety of specialties (e.g. Endocrinology, Cardiovascular Physiology, Neurophysiology, Respiratory Physiology, Reproductive Physiology, Sensory Physiology), each with a wide variety of technical and analytical methods. More information is available on the departmental website (www.physiology.utoronto.ca).

Undergraduate Coordinator: Dr. M.B. French, Medical Sciences Building, Room 3368 (416-978-8712)

Undergraduate Assistant: Eva Eng, Medical Sciences Building, Room 3209, eva.eng@utoronto.ca, (416-978-5077)

Physiology Programs

Biological Physics: see Physics

Physiology Specialist (Science program)

Physiology Specialist program (14 full courses or their equivalent)

The Physiology Specialist program is a Type 3 program. Only students with an average of at least 70% in the required first-year courses and a minimum of 60% in each of these courses will be considered for entrance into the specialist program. Enrolment is limited and selection is based on performance in the following first-year required courses: BIO130H1, (CHM135H1/CHM139H1), (CHM136H1/CHM138H1) or their equivalents, and 1.5 full course equivalents from: BIO120H1, MAT135H1, MAT136H1, MAT137Y1, MAT157Y1, PHY131H1, PHY132H1, PHY151H1, PHY152H1. Students apply via the Faculty’s Program Enrolment website. See the Arts & Science Program Enrolment website for application procedures. For more information, refer to the Physiology website at www.physiology.utoronto.ca.

First Year: (4 full course equivalent from the following)
BIO120H1/PSL190H1, BIO130H1; (CHM135H1/CHM139H1),(CHM136H1/CHM138H1), (PHY131H1, PHY132H1)/(PHY151H1, PHY152H1)

First Year or upper years:
(MAT135H1, MAT136H1)/MAT137Y1/MAT157Y11

Second Year:
1. 2.5 full course equivalents from BCH210H1; BIO230H1/BIO255H1; CHM220H1/CHM247H1/CHM249H1; PSL300H1, PSL301H1
2. 1.5 full course equivalents from BIO220H1, BIO260H1/HMB265H1; MAT235Y1, PHY231H1, PSL299Y1, STA220H1/STA250H1

Third Year:
1. 3 full course equivalent from BCH370H1; PSL304H1, PSL305H1, PSL350H1/CSB349H1/BCH311H1, PSL372H1, PSL374H1
2. 1 full course equivalent from the following list: ANA300Y1; BME498Y1; CSB325H1, CSB332H1/CJH332H1, CSB343H1, CSB345H1/CSB445H1, CSB346H1, CSB347H1; IMM340H1/IMM341H1, IMM350H1/IMM351H1; PCL201H1, PCL285H1, PCL302H1; PHY331H1, PSL378H1/PSL379H1; PSY397H1

Fourth Year: (at least 2 FCEs at 400-level)
1. PSL498Y1/PSL499H1
2. 1-1.5 full course equivalents from PSL400-series or HMB430H1/HMB470H1/HMB472H1

1These courses may be taken in the first year or subsequent years, and are not required for entrance into the specialist program.

Physiology Major (Science Program)

This is a limited enrolment program that can only accommodate a limited number of students. Eligibility will be competitive and based on a student’s marks in the 3.0 FCE required first-year courses:

BIO120H1, BIO130H1, (CHM135H1/CHM139H1), (CHM136H1/CHM138H1)/CHM151Y1, and 1.0 FCE from any of the following: MAT135H1, MAT136H1, MAT135Y1, MAT137Y1, MAT157Y1, PHY131H1, PHY132H1, PHY151H1, PHY152H1 with an average of at least 70% on these 3.0 full-course equivalents (FCEs) and a final mark of at least 60% in each course.

While it is difficult to predict what will be competitive course marks and average in a given year, based on previous years, the estimate is: course marks = mid 70s; average = mid 70s.

Achieving these estimated marks does not guarantee admission to the program in any given year.

Note:  Students must apply to this program on the Arts & Science Faculty Registrar’s Office website (see the Arts & Science Program Enrolment website for application procedures).

(8 full courses or their equivalent, including 0.5 FCE at the 400-level)

First Year:
1. 2 full course equivalent from (BIO120H1, BIO130H1)/BIO150Y1; (CHM135H1/CHM139H1), (CHM136H1/CHM138H1)/CHM151Y
2. 1 full course equivalent from any of the following: MAT135H1, MAT136H1, MAT135Y1, MAT137Y1, MAT157Y1, PHY131H1, PHY132H1, PHY151H1, PHY152H1

Second Year:
2 full course equivalent from BCH210H1; BIO230H1/BIO255H1; PSL300H1, PSL301H1

Higher Years:
1. 1 full course equivalent from PSL372H1, PSL350H1/BCH311H1/CSB349H1
2. 1 full course equivalent from ANA300Y1; CSB325H1, CSB330H1, CSB332H1/CJH332H1, CSB343H1, CSB345H1/CSB445H1, CSB346H1, CSB347H1; IMM340H1/IMM341H1, IMM350H1/IMM351H1; NFS284H1; PCL201H1, PCL285H1, PCL302H1; PSY201H1; PSY397H1; STA220H1
3. 1 full course equivalent from HMB430H1/HMB470H1/HMB472H1; PSL304H1, PSL305H1, PSL374H1, PSL378H1/PSL379H1, PSL380H1, PSL400-series courses

Physiology Minor (Science program)

(4 full courses or their equivalent; one 300+ level FCE must be included in the program)

1. 2 full course equivalents from: (BIO120H1, BIO130H1)/BIO150Y1; PSL201Y1/(PSL300H1, PSL301H1)
2. 2 full course equivalents from: BIO251H1, BIO270H1, BIO271H1; CSB325H1, CSB332H1/CJH332H1, CSB343H1, CSB344H1, CSB345H1/CSB445H1, CSB346H1, CSB347H1; EEB328H1; HMB200H1/HMB220H1, HMB430H1, HMB470H1, HMB472H1; PSL280H1, PSL299Y1, PSL 300-series, PSL400-series;  PSY290H1, PSY396H1, PSY397H1, PSY399H1, PSY490H1, PSY492H1, PSY494H1, PSY497H1

Physiology Courses


First Year Seminars

The 199Y1 and 199H1 seminars are designed to provide the opportunity to work closely with an instructor in a class of no more than twenty-four students. These interactive seminars are intended to stimulate the students’ curiosity and provide an opportunity to get to know a member of the professorial staff in a seminar environment during the first year of study. Details can be found at www.artsci.utoronto.ca/current/course/fyh-1/.


PSL190H1    Biomedical Research at the Cutting Edge[24L/6S]

Explore the thought processes, logic, motivation, techniques, analysis and impact of recent high-profile publications to gain insight into the enterprise of science. Outstanding scientists present recent high-impact papers, and students will examine the research in depth, focusing on the underlying questions, experimental approach, results and significance.

Prerequisite: SBI4U and SCH4U (Grade 12 University Preparation Biology and Chemistry); permission of Department
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL201Y1    Basic Human Physiology[48L]

A survey course intended for students who are not proceeding further in Physiology.

Exclusion: Any 300-level PSL course taken previously or concurrently
Recommended Preparation: 100-level course in BIO or equivalent
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL280H1    Introduction to Physiologic Adaptations of Marine Mammals[24L/14P]

Systems approach to physiology of marine mammals in their aquatic environment. Highlights unique features of cardiovascular, respiratory, renal, urinary, and reproductive systems. Introduces relevant physiology, and makes comparisons to human condition and disease.

Prerequisite: (BIO120H1, BIO130H1)/BIO150Y1, CHM138H1/CHM151Y1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL299Y1    Research Opportunity Program

Credit course for supervised participation in faculty research project. Details at http://www.artsci.utoronto.ca/current/course/rop. Not eligible for CR/NCR option.

Distribution Requirement Status: Science
Breadth Requirement: None

PSL300H1    Human Physiology I[36L/5T]

Principles of neurophysiology, endocrinology and reproductive physiology for students enroled in Life Science programs.

Exclusion: PSL201Y1, PSL302Y1
Recommended Preparation: BIO130H1/BIO150Y1; CHM138H1/CHM151Y1; and 1 FCE from any of the following: MAT135H1, MAT136H1, MAT135Y1, MAT137Y1, MAT157Y1, PHY131H1, PHY132H, PHY151H1, PHY152H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL301H1    Human Physiology II[36L/4T]

Principles of respiratory, cardiovascular, gastrointestinal, and renal physiology for students enroled in Life Science programs.

Exclusion: PSL201Y1, PSL302Y1
Recommended Preparation: BIO130H1/BIO150Y1; CHM138H1/CHM151Y1; and 1 FCE from any of the following: MAT135H1, MAT136H1, MAT135Y1, MAT137Y1, MAT157Y1, PHY131H1, PHY132H, PHY151H1, PHY152H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL304H1    Topics in Cellular, Molecular and Organismic Physiology I[32L/16T]

Control systems, feedback, networks, and both neonatal and adult cardiovascular and respiratory control are the topics examined in detail using homeostasis as a unifying theme. Tutorials involve computer simulations, case studies and/or experimental design. This course is designed for students in the Physiology Specialist and Biological Physics Specialist Programs, although permission is granted to students in other programs upon approval by the Department.

Prerequisite: BCH210H1, PSL300H1, PSL301H1, MAT100-series, PHY100-series
Exclusion: PSL303Y1
Recommended Preparation: PSL372H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL305H1    Topics in Cellular, Molecular and Organismic Physiology II[32L/16T]

Molecular, cellular and organismic physiology of the central nervous system, gut, pancreas and glucose-sensing tissues; CNS diseases, obesity and diabetes are used as model systems. Tutorials involve computer simulations.  This course is designed for students in the Physiology Specialist and Biological Physics Specialist Programs, although permission is granted to students in other programs upon approval by the Department.

Prerequisite: BCH210H1, PSL300H1, PSL301H1, MAT100-series
Exclusion: PSL303Y1
Recommended Preparation: PSL372H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL350H1    Mammalian Molecular Biology[18L/12T/6S]

Extend molecular biology concepts to current scientific literature in mammalian physiology. Apply these principles to disease and complex behaviours. Discuss bioethical issues raised by these techniques and their application. Benefit from three weeks in small group seminars lead by research professors focusing on current advances in mammalian molecular biology.

Prerequisite: BIO230H1, PSL300H1, BCH210H1
Corequisite: PSL301H1
Exclusion: BCH311H1/BIO349H1/CSB349H1/MGY311Y1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL372H1    Mammalian Physiology Laboratory[12L/36P]

A laboratory course covering selected topics in physiology.

Prerequisite: BIO230H1/BIO240H1, BIO241H1)/BIO255H1, BCH210H1/BCH242Y1, MAT100-series/PHY100-series, PSL300H1, PSL301H
Corequisite: BCH370H1 (recommended)
Exclusion: CSB348H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL374H1    Advanced Physiology Laboratory[12L/36P/12S]

A problem-based laboratory course focused on the integration and control of organ systems to understand body functions.  Enrollment in this course is restricted to students in the Physiology Specialist and Major Programs although permission is granted to students in other programs upon approval by the Department.

Prerequisite: BIO230H1/(BIO240H1, BIO241H1)/BIO255H1, PSL300H1, PSL301H1, PSL372H1
Exclusion: CSB348H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL378H1    Field Physiology: Marine Mammal Autopsy[12L/24T/36P]

An opportunity to go outside of the traditional university classroom and actively participate in a marine mammal autopsy. Learn the diversity and adaptive nature of marine mammalian physiology/anatomy as it compares to human. The course is 2 weeks (in May), one week of hands-on tissue dissection, and one week of group discussions of the findings and draft report preparation. Not eligible for CR/NCR option.

Prerequisite: BIO270H1, BIO271H1/PSL201Y1/PSL280H1/PSL300H1, PSL301H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL379H0    Comparative Marine Mammal Physiology in the Field[24T/36P]

Hands-on monitoring of physiological measures with live dolphins, manatee and sea lions; field observations and applied learning to a physiology project. Two-weeks at the end of April early May: 1st week at marine research center in Mexico, 2nd week of wrap-up discussion and integration of data at U of T. Not eligible for CR/NCR option.

Prerequisite: BIO220H1/BIO230H1/BIO270H1/BIO271H1/CSB343H1/PSL280H1/PSL201Y1/PSL300H1/PSL301H1/PSY362H1/any other relevant course
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL398H0    Research Excursions[TBA]

An instructor-supervised group project in an off-campus setting. Details at http://www.artsci.utoronto.ca/current/course/399. Not eligible for CR/NCR option.

Distribution Requirement Status: Science
Breadth Requirement: None

PSL399Y0    Research Excursions[TBA]

An instructor-supervised group project in an off-campus setting. Details at http://www.artsci.utoronto.ca/current/course/399. Not eligible for CR/NCR option.

Distribution Requirement Status: Science
Breadth Requirement: None

PSL404H1    Regenerative Medicine[24L/12T]

Regenerative medicine promises to restore body function that has been lost due to disease, damage or age. Students will explore selected molecular, stem cell and tissue engineering developments to better understand how the body normally functions and how cells, tissues, and organs can be repaired or replaced.

Prerequisite: PSL300H1, PSL301H1
Recommended Preparation: PSL350H1/BCH311H1/CSB349H1/MGY311Y
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL420H1    Reproduction I: Development and Function[24L]

This course provides an in-depth review of the development and function of the male and female reproductive systems. Topics include sex determination and differentiation, steroidogenesis, gametogenesis, hormonal control of the reproductive axis, the female ovulatory cycle, fertilization and implantation, infertility and assisted reproduction approaches.

Prerequisite: PSL300H1, PSL301H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL421H1    Reproduction II: Pregnancy and Birth[24L]

General overview of the integrated physiologic events associated with pregnancy and birth. The approach emphasizes physiologic processes using insights gained from studies of humans, animals, cells and genes. Where appropriate the clinical consequences of aberrant development are reviewed.

Prerequisite: PSL300H1, PSL301H1
Recommended Preparation: PSL420H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL425H1    Integrative Metabolism and its Endocrine Regulation[24L]

This course integrates the newest findings and experimental approaches from cellular and molecular biology into metabolic function at the tissue, organ and whole body level.

Prerequisite: BCH210H1, PSL300H1, PSL301H1
Recommended Preparation: PSL305H1/PSL303Y1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL432H1    Theoretical Physiology[24L]

Theoretical treatment of neurophysiology. Mathematical modeling and analysis of neurophysiological systems.

Prerequisite: MAT235Y1/MAT237Y1; APM346H1/MAT244H1
Recommended Preparation: PHY200-series; PSL201Y1/PSL300H1/(BIO270H1, BIO271H1)
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL440Y1    Neuroscience I: Systems and Behaviour[96L]

Introduction to systems neuroscience. A review of basic neuroanatomy and physiology followed by in-depth study of selected sensory and motor systems, with an emphasis on clincial applications in the second term. Students with an elementary neuroscience background progress to reading neuroscience literature on their own.

Prerequisite: PSL300H1/PSY290H1/CSB332H1 or equivalent
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL444Y1    Neuroscience II: Cellular and Molecular[72L]

Overview of the fundamentals of cellular and molecular aspects of brain function. Course material is updated yearly to reflect the rapid evolution of ideas in Neuroscience.

Prerequisite: PSL300H1, PSL301H1, CSB332H1 or permission of instructor
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL450H1    Mechanisms of Neural and Endocrinal Secretion[24L]

Exocytosis and other aspects of secretion mainly in neurons and neuroendocrine cells, but also in pancreatic cells. Topics include synapse anatomy and physiology, synaptic plasma membrane and vesicle proteins, membrane fusion, genetic tools, endocrine secretion, plasticity in neurotransmitter release, diseases arising from secretion defects.

Prerequisite: BCH210H1, PSL300H1/(BIO240H1, BIO241H1), PSL350H1/CSB349H1/BCH311H1/MGY311Y1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL452H1    Membrane Physiology[24L]

Biophysics and molecular biology of ion channels. Topics include equivalent circuits for cells, molecular structure of voltage-gated channels, distribution of channels, relationship between single-channel and whole-cell recording, and regulation of channel function by voltage, phosphorylation, G-proteins and metabolites.

Prerequisite: PSL300H1, PSL301H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL462H1    Molecular Aspects of Cardiovascular Function[36L]

Heart anatomy and development, ion channels and contractile proteins involved in cardiac and smooth muscle contraction are studied. Emphasis is on regulation of electrical and contractile function of kinases, metabolism, volume and ions.

Prerequisite: PSL300H1, PSL301H1, PSL304H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL470H1    Developmental Cardiovascular Physiology[24L]

Development of the cardiovascular system from conception to adulthood with particular emphasis on maturational changes, age-related differences and developmental problems from cellular/molecular to whole organ/system.

Prerequisite: PSL300H1, PSL301H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL472H1    Sleep Physiology and Chronobiology[24L]

This course covers the physiology underlying sleep and circadian rhythms, and their impact on important physiological processes and health.  The integrative nature of the basic physiological processes is emphasized via discussions and clinical presentations.  Overall, the aim is to present the full spectrum of integrative physiology from molecules and cells to understanding the sick patient.

Prerequisite: PSL300H1, PSL301H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL480H1    Diving Physiology of Marine Mammals[24L/6T]

This course compares and contrasts the physiological and anatomical adaptations exhibited by the different species of marine mammals in relationship to humans, with respect to diving.

Prerequisite: (BIO270H1, BIO271H1)/PSL201Y1/PSL300H1, PSL301H1; PSL280H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL495H1    Communicate Biomedical Science[6L/2T/18S]

Research, critique and write a manuscript on a topic of your choice in the scientific literature while guided by classes and assignments that develop advanced science communication skills; and by a mentor expert in your area of clinical or basic physiology.

Prerequisite: PSL300H1; PSL301H1; PSL372H1; 13.5 additional credits; and permission of Department
Exclusion: BCH479H1; HMB490H1; HMB491H1
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL498Y1    Project in Physiology[144P]

Laboratory research project with reading assignments leading to a final report. By special arrangement with a Physiology staff member after admission to course. PSL498Y1 is recommended for students applying to the Physiology graduate program.  Enrollment in this course is restricted to students in the Physiology Specialist and Major Programs, although permission is granted to students in other programs upon approval by the Department. Not eligible for CR/NCR option.

Prerequisite: (PSL304H1, PSL305H1)/PSL303Y1, PSL372H1, PSL374H1, permission of Department
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)

PSL499H1    Project in Physiology[72P]

Laboratory research project with reading assignments leading to a final report. By special arrangement with a Physiology staff member after admission to course. PSL499H1 is recommended for students applying to the Physiology graduate program.  Enrollment in this course is restricted to students in the Physiology Specialist and Major Programs, although permission is granted to students in other programs upon approval by the Department. Not eligible for CR/NCR option.

Prerequisite: (PSL304H1, PSL305H1)/PSL303Y1, PSL372H1, PSL374H1, permission of Department
Distribution Requirement Status: Science
Breadth Requirement: Living Things and Their Environment (4)