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PSL PhysiologyOn this page: Introduction | Faculty Members | Programs | Courses See also: Course Summer Timetable | Course Winter Timetable | Secondary School Information | More on Department IntroductionPhysiology is the study of living matter in action, i.e., the study of function by physical means or chemical means. It is an integrating discipline dealing with correlating and integrating mechanisms, with controls, compensations, and interrelationships. Interaction with the environment is a major factor in Physiology. Physiology serves as a bridge between cellular biology, control theory and systems analysis. Physiology provides a necessary background for the study of Pharmacology; a preparation for graduate work in Physiology and related areas; for the teaching of Biological Science in secondary schools; or for subsequent training in Medicine, Dentistry, Pharmacy, Nursing, and the Health Sciences in general. Physiologists are needed also in hospitals and departments of medicine as teachers and research personnel, as well as in research institutes and governmental laboratories. Other outlets would be in agriculture and veterinary schools and in military research establishments. The development of air and space travel, the exploration of the continental shelf, the development of Northern regions, and increased emphasis on exercise and fitness, all provide problems and research opportunities for the person trained in Physiology. Physiology at the research level covers a variety of specialties (e.g. Endocrinology, Cardiovascular Physiology, Neurophysiology, Respiratory Physiology, Renal Physiology, Sensory Physiology), each with very different technical and analytical methods. Skill in some other science is often an advantage and the undergraduate student who intends to specialize in Physiology will find it desirable to supplement the program by an appropriate pattern of courses selected from the subjects of Biochemistry, Chemistry, Computer Science, Electronics, Mathematics, Pharmacology, Physics, Statistics, Zoology. An Undergraduate Brochure is available. Undergraduate Secretary: Professor W.A. MacKay, Medical Sciences Building (978-2675) Enquiries and Counselling: Medical Sciences Building, Room 3209 (978-8779)
PHYSIOLOGY PROGRAMSPHYSIOLOGY (B.Sc.)Enrolment in this Program is limited. Selection is based on GPA in first and second year required courses. See application procedure under BMS programs. Specialist program (Hon.B.Sc.): S04821 (14 full courses or their equivalent, including at least one 400-series course)
Minor program Minor program: R04821 (4 full courses or their equivalent) Enrolment in this Program requires the completion of 4 courses; no minimum GPA required. One 300-series course must be included in the program.
PHYSIOLOGY (THEORETICAL) (Hon.B.Sc.)Enrolment in this Program is limited. Selection is based on GPA in first and second year required courses. See application procedure under BMS programs.
Specialist program: S14291 (16 full courses or their equivalent, including at least one 400-series course)
PHYSIOLOGY COURSES(see Section 4 for Key to Course Descriptions)For Distribution Requirement purposes, all PSL courses are classified as SCIENCE courses.
PSL201Y A survey course intended for students who are not proceeding further in Physiology. A course fee of $3.00 is required and is payable with tuition.
PSL299Y Credit course for supervised participation in faculty research project. See Research Opportunity Program for details.
PSL302Y Principles of Human Physiology for students enroled in Basic Medical Science programs. A course fee of $7.00 is required and is payable with tuition.
PSL303Y Using homeostasis and feedback as a unifying theme, topics in control systems, cell signalling, rhythms, muscle contraction, movement and environmental adaptations are examined. Tutorials use computer simulations and problem sets. A course fee of $16.00 is required and is payable with tuition.
PSL372H A laboratory course covering selected topics in physiology. A course fee of $14.00 is required and is payable with tuition.
PSL374H A problem-based laboratory course focussed on the integration of organ systems to understand the control mechanisms of body function. A course fee of $14.00 is required and is payable with tuition.
PSL420H This course provides an in-depth review of the development and function of the male and female reproductive systems. Topics include sex determination and differentiation, gametogenesis, hormonal control of the reproductive systems, the female ovulatory cycle, seasonal breeding, sexual behaviour, fertilization and implantation.
PSL421H General overview of the integrated physiologic events associated with pregnancy and birth. The approach emphasizes physiologic processes using insights gained from studies of humans, animals, cells and genes. Where appropriate the clinical consequences of aberrant development are reviewed.
PSL424H Selected topics in the fields of Neuroendocrinology, Steroid Endocrinology and the regulation of energy metabolism illustrate the general principles underlying the control of complex endocrine systems. Particular emphasis is placed on the evolutionary development of hormone systems through gene duplication and differentiation.
PSL431H General computer and mathematical techniques applied to physiology. FORTRAN/BASIC programming, solution of ordinary differential equations, curve fitting, linear systems analysis.
PSL432H Theoretical treatment of physiology. Mathematical modelling and advanced analysis of physiological systems.
PSL433H Mathematical and computational analysis of electrical behaviour of biological neurons and networks. Emphasis is on deriving and solving models from the literature and comparing them with experimental results. The course is suitable for computer-literate biology students. Included: tutorial on electrical circuits, computer lab.
PSL440Y Introduction to systems neuroscience. A review of basic neuroanatomy and physiology followed by in-depth study of selected sensory and motor systems. Students with an elementary neuroscience background progress to reading neuroscience literature on their own.
PSL441H Optics, pattern perception, eye movements, and electrophysiology, at graduate level.
PSL443H Control of body movement and posture by the nervous system in normal and pathological conditions. Topics include nonlinear dynamical systems, central pattern generators in the cerebral cortex, brainstem and spinal cord, reflexes, and basal ganglia-cerebellar function.
PSL444Y Overview of the fundamentals of cellular and molecular aspects of brain function. Course material is updated yearly to reflect the rapid evolution of ideas in Neuroscience.
PSL452H Biophysics and molecular biology of ion channels. Topics include equivalent circuits for cells, molecular structure of voltage-gated channels, distribution of channels, relationship between single-channel and whole-cell recording and regulation of channel function by voltage, phosphorylation, G-proteins and metabolites.
PSL454H A practical approach to instrumentation as a preparation for using sophisticated measurement systems. A course fee of $5.00 is required and is payable with tuition.
PSL460H An overview of the ways in which techniques in molecular biology are being used to resolve current issues in physiology. The systems to be studied include individual cells, organ systems, integrated systems, and whole animal physiology and pathophysiology. A course fee of $5.00 is required and is payable with tuition.
PSL461H An overview of recent developments in the area of molecular and cellular neurobiology. The course emphasizes the results of molecular biological studies aimed at determining the structure and function of the proteins that control crucial processes in the function of the nervous system. A course fee of $8.00 is required and is payable with tuition.
PSL462H Heart anatomy and development, ion channels and contractile proteins involved in cardiac and smooth muscle contraction are studied. Emphasis is on regulation of electrical and contractile function of kinases, metabolism, volume and ions.
PSL470H Development of the cardiovascular system from conception to adulthood with particular emphasis on maturational changes, age-related differences and developmental problems from cellular/molecular to whole organ/system.
PSL471H In-depth study of specific topics in human physiological response to conditions such as altitude, cold, exercise and birth. Students are required to make field trips to physiological laboratories on campus and at the Defence and Civil Institute of Environmental Medicine.
PSL497H Students learn to read, write and speak about current research in Physiology. A course fee of $3.00 is required and is payable with tuition.
PSL498Y /499H Project in Physiology 156P/78P Laboratory research project with reading assignments leading to a final report. By special arrangement with a Physiology staff member after admission to course. PSL498Y is recommended for students applying to the Physiology graduate program.
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