A & S Calendar 1998-99: IMM IMMUNOLOGY

Arts & Science Calendar 1998-99: Table of Contents: Programs and Courses

IMM IMMUNOLOGY

Introduction

Immunology is a new branch of the medical sciences which has recently gained prominence as a field of study in its own right, but which continues to draw on the more traditional disciplines of Microbiology, Pathology and Biochemistry. In essence, Immunology is the study of the physiological responses which result when foreign (i.e. non-self) materials are introduced into a vertebrate organism such as man. Traditionally, the discipline has focussed on the body's response to infectious micro-organisms, with the purpose of developing effective vaccines. However, the scope of modern Immunology now encompasses all aspects of self vs. non-self recognition phenomena including organ transplantation, tumour immunology and autoimmune diseases. Recent major advances in our understanding of the cellular and molecular basis of the immune response promise to provide us with a new generation of prophylactic, therapeutic and diagnostic reagents of relevance to human and animal health.

The Department of Immunology in collaboration with Trinity College co-ordinates a specialist program in Immunology. The emphasis of this program is to provide students with a sound theoretical understanding of the cellular and molecular basis of non-self recognition, together with sufficient laboratory experience to enable the students to consider embarking on a career in the discipline. Immunologists may have careers in universities and other centres of learning and research, as well as in the biotechnology industries, diagnostic laboratories and various government agencies.

Courses in this specialist program are drawn from offerings by the Department, together with courses from other Departments, taught in some cases by members of the Department of Immunology. As enrolment in the specialist program is restricted, please consult the Co-ordinator.

Undergraduate Secretary: Dr. B.H. Barber (978-6959)

Enquiries: Department of Immunology, Room 5271, Medical Sciences Building (978-8360)

Faculty Members

Collaborative Programs of the Faculty of Arts and Science & the Faculty of Medicine

Professor Emeritus
B. Cinader, Ph D, D Sc, OC, FRSC
Professor and Acting Chair of the Department
M.H. Julius, B Sc, Ph D University Professor
T.W. Mak, Ph D, D Sc, FRSC
Professors
B.H. Barber, M Sc, Ph D	R.H. Painter, B Sc, Ph D
H.M. Dosch, MD	J.C. Roder, BA, Ph D
R.M. Gorczynski, Ph D, MD	C. Roifman, MD
J.B. Hay, M Sc, Ph D	D. Sauder, MD
N. Hozumi, Ph D, MD	M.J. Shulman, BA, Ph D
R.D. Inman, BA, MD	K.H. Shumak, M Sc, MD, FRCP (C)
N.N. Iscove, Ph D, MD	E. Silverman, MD
D.E. Isenman, B Sc, Ph D	K. Siminovitch, MD, FRCP, ABIM
E.C. Keystone, B Sc, Ph D	J. Wade, B Sc
M.V. Letarte, B Sc, Ph D	T.H. Watts, B Sc, Ph D
G. Levy, B Sc, MD, FRCP	D. Williams, M Sc, Ph D
R.G. Miller, M Sc, Ph D	G.E. Wu, M Sc, Ph D
C. Paige, B Sc, Ph D
Associate Professors
N. Berinstein, MD	S. Lewis, BS, PhD
J.M. Boggs, M Sc, Ph D	A. Leznoff, M Sc, Ph D
A. Cohen, M Sc, Ph D	P.S. Ohashi, B Sc, Ph D
J. Danska, AB, Ph D	C.A. Ottaway, Ph D, MD, LMCC, FRCP
E. Fish, M Sc, Ph D	P. Poussier, MD
C. Guidos, B Sc, Ph D	L. Rubin, MD, LMCC, FRCP (C)
J. Jongstra, M Sc, Ph D	P. Vadas, B Sc, Ph D, MD
Assistant Professors
S. Berger, M Sc, Ph D	E. Nisbet-Brown, Ph D, MD
J.W. Chamberlain, M Sc, Ph D	J. Penninger, MD
P.J. Doherty, B Sc, Ph D	R. Rottapel, MD
J. Jongstra-Bilen, M Sc, DEA, Ph D	F. Tsui, M Sc, Ph D
C. Laskin, B Sc, MD	J. Wither, B Sc, MD, Ph D
C. Lau, M Sc, Ph D (Adjunct)	J.C. Zúñiga-Pflücker, B Sc, Ph D

IMMUNOLOGY PROGRAMS

IMMUNOLOGY (Hon.B.Sc.) Sponsored by the Department of Immunology, Faculty of Medicine, and Trinity College; consult Dr. B.H. Barber (978-6959)

Enrolment in this Program is limited and admission is based on a GPA of 2.7 in the preceding year and on marks obtained in the four required First Year courses.

Specialist program: S10021 (13.5 full courses or their equivalent, including at least one 400-series course)
First Year: BIO 150Y; CHM 137Y/151Y; MAT 135Y/137Y; PHY 110Y/138Y/140Y (PHY 138Y recommended)
Second Year: BIO 250Y; CHM 222Y/223Y, CHM 240Y

Third Year: BCH 321Y; IMM 334Y; MGB 311Y; MPL375Y

Fourth Year:
1. JBI 428H; IMM 430H, 435H
2. IMM 450Y or one full course equivalent at the 400-series level in ANA, BCH, LMP, MGB, MPL or ZOO

IMMUNOLOGY COURSES

(see Section 4 for Key to Course Descriptions)

For Distribution Requirement purposes, all IMM courses are classified as SCIENCE courses.

IMM299Y
Research Opportunity Program

Credit course for supervised participation in faculty research project. See Research Opportunity Program for details.

IMM334Y
Introductory Immunology 52L

The basic principles of immunology; tissues and cells of the immune system; cell biology of the humoral and cell-mediated immune responses; immunogenetics; immunoglobulin structure, function and biosynthesis; immunological techniques; immunopathology; infection and immunity; transplantation, autoimmunity and tumour immunology.
Prerequisite: BIO250Y

JBI428H
Molecular Immunology 26L

Molecular mechanisms involved in the generation and expression of specific immunity including the structure, function and biosynthesis of immunoglobulins, the complement systems, transplantation antigens and membrane signalling events. (Given by the Departments of Biochemistry and Immunology)
Prerequisite: BCH310H/321Y, IMM334Y

IMM430H
Advanced Immunobiology 26L

Hemopoiesis, lymphopoiesis, a study of the cells involved in the immune response including their ontogeny, physical and chemical characteristics, the nature of cellular interactions which govern the expression of immunity and self tolerance, the nature of the effector cells in immunity and genetic control of immune responses.
Prerequisite: IMM334Y, JBI428H

IMM435H
Practical Immunology 72P

Application of basic principles acquired from IMM334Y; immunological procedures used in research and diagnostic laboratories; rudiments of etiology, pathogenesis, and laboratory diagnosis of diseases of immune system; principles of immunological diagnostic procedures in some infectious diseases; instruction through lectures, practical exercises, video tapes, student presentations.
Prerequisite: BCH310H/321Y, IMM334Y

IMM450Y
Research Project in Immunology 154P

An opportunity for specialized research in Immunology under the supervision of a member of the Faculty.
Prerequisite: IMM334Y and permission of the Course Coordinator

We welcome your comments and enquiries.
Revised: April 6, 1998