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Biochemistry is concerned with the study of the living organism at the molecular level. Since Biochemistry is central to many biological and medical sciences, students undertaking studies in these diverse areas often find a background in biochemistry essential. A Specialist program in Biochemistry is offered.
Enrolment in the Biochemistry Specialist Program is limited. For further information consult the Undergraduate Secretary.
Undergraduate Secretary: L.A. Moran (978-2704) (firstname.lastname@example.org)
Enquiries: Medical Sciences Building, Room 5207 (978-2700)
Enrolment in this Program requires the completion of the first two years of a science program including three prerequisite second-year courses. Enrolment into the Biochemistry Specialist Program at the end of second year is limited to no more than 50 students. Selection is based in part on the GPA in the first- and second-year courses and performance in selected prerequisite courses.
Specialist program: S17621 (14 full courses or their equivalent, including at least one 400-series course)
NOTE: CHM 229H has MAT 235Y/237Y as co-requisite
NOTE: Students who take CHM 229H in 2nd year must take CHM 327Y in third yearSection 4 for Key to Course Descriptions)
For Distribution Requirement purposes, all BCH courses are classified as SCIENCE courses.
Credit course for supervised participation in faculty research project. See Research Opportunity Program for details.
An introductory course in biochemistry intended for students who are NOT taking BCH321Y as part of their program. The course is divided into three sections, covering proteins and enzymes, metabolism, and the structure of nucleic acids.
An introductory course in biochemistry. Intended for students specializing in biochemistry and related programs, and requiring a more intensive background in chemistry than BCH310H.
Techniques in biochemical research and analytical laboratories. Intended for students who are not proceeding further in biochemistry. (Enrolment limited)
An introduction to laboratory techniques of modern biochemistry. Experiments illustrate and develop the concepts described in BCH321Y, and prepare the student for advanced training in biochemical laboratory techniques. (Enrolment limited)
NOTE Students who have completed BCH310H/320Y or Erindale CHM361H and 362H may enrol in 400-series lecture courses if they obtain permission of the Department
Elements of protein structure and conformations are presented, and their role in protein functions is discussed in detail. Proteins as enzymes are described, and the structures and functions os membrane proteins are discussed. Recent advances in protein engineering, and site-directed mutagenesis are presented. (Enrolment limited)
Structure and biogenesis of cell surface membranes; relationship of structure to functional aspects of the cell surface, cell-cell interactions, transmembrane signals, hormone receptors, cell surface enzymes and transport.
Mechanisms of control of mammalian intermediary metabolism. Kinetics of feedback, allosteric proteins and enzymes; control of carbohydrate, lipid, amino acid, and nucleotide metabolism; relationship between metabolism and cell growth. (Offered in alternate years)
The application of mechanistic chemistry to enzyme systems. Catalysis, chemical model systems, coenzymes, metals, covalent catalysis. (Offered in alternate years)
Theory and practice of modern biophysical techniques as applied in the study of structure and function of macromolecules; emphasis on protein X-ray crystallography, NMR, and other spectroscopic methods; discussion of selected examples.
Molecular mechanisms involved in the generation and expression of specific immunity including the structure, function and biosynthesis of immunoglobulins, the complement systems, transplantation antigens and membrane signalling events. (Given by the Departments of Biochemistry and Immunology)
Recommended preparation: JLM349H/MGB311Y
Structure, chemistry, and occurrence in biological systems of glycerides, phospholipids, glycolipids, and sterols, and aspects of their metabolism. Physical chemistry of complex lipids, principles governing assembly into bilayer membranes, and methods for studying membrane structure. (Offered in alternate years)
The objective of the course is to introduce students to the chemistry of nucleic acids and nucleo proteins and how structure affects their functions as the reservoir of genetic information and as structural elements in biological systems.
Experiments demonstrating modern concepts of biochemistry and molecular biology. (Enrolment limited)
Research in a particular area of biochemistry, by arrangement with the Department and the instructor concerned.
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