Pharmacology and Toxicology Courses |
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First Year Seminars The 199Y1 and 199H1 seminars are designed to provide the opportunity to work closely with an instructor in a class of no more than twenty-four students. These interactive seminars are intended to stimulate the students’ curiosity and provide an opportunity to get to know a member of the professorial staff in a seminar environment during the first year of study. Details here. PCL102H1 This course introduces students to the processes and strategies for discovering new drugs with a special focus on current and emerging approaches for the rational design of drugs that are both effective and safe. PCL201H1 A general introduction to pharmacology and pharmacokinetics. Topics include: absorption, distribution, biotransformation, elimination, calculation of dosages and pharmacokinetic parameters, variability in drug response, adverse drug reactions and special interest topics. PCL299Y1 Credit course for supervised participation in faculty research project. Details here. PCL302H1 Topics include biological action of drugs on membranes, enzymes, receptors, neural and hormonal systems, transmission and modulation. PCL362H1 Toxicological problems encountered in animals and humans; biochemical mechanisms and clinical factors of toxicological significance; models of drug-related diseases. PCL365Y1 A hands-on laboratory course exploring a wide variety of modern experimental techniques currently utilized in toxicology. This course will provide the experimental theory of how the techniques work and their advantages and disadvantages, while additionally allowing students to perform these techniques in the process of addressing toxicological problems. Enrollment in this course is generally restricted to students enrolled in the Biomedical Toxicology Specialist, Pharmacology and Toxicology Double Specialist, and Environment and Toxicology Specialist programs. PCL376H1 A practically oriented course, focused on experimental design and the analysis of pharmacological and toxicological data. Topics include: principles of experimental design, data analysis and statistical tests appropriate for each type, use of computing statistical packages, analysis of dose-response and time-response curves and analysis of receptor binding assays. PCL389H1 This service learning course explores issues surrounding the effects that pharmaceuticals and chemicals have in society. Specifically, it integrates pharmacology with social, health and political issues as they relate to drug abuse and addiction. Students are required to interact and work with community partners during the semester. Classroom discussions will integrate community experiences with lecture material. PCL470Y1 Concepts of drug properties and their interaction with living systems and their constituent parts will be discussed. Mechanism of action and pharmacological properties of drugs acting on the autonomic and central nervous systems, cardiovascular, renal, respiratory, gastrointestinal, immunological and endocrine systems; endogenous compounds; antimicrobial and anti-inflammatory drugs, chemotherapy, pharmacogenomics and special topics in pharmacology. PCL471Y1 Demonstrations, seminars, and laboratory exercises in selected areas of pharmacology. Enrollment in this course is generally restricted to students enrolled in the Pharmacology Specialist and Double Specialist programs. PCL472Y1 This course affords students an opportunity for hands-on research experience in a laboratory or applied pharmacology setting. Students will work under the supervision of a faculty member and will submit a final written report. Enrollment is limited and requires permission from the Department of Pharmacology and Toxicology. It is the student’s responsibility to secure a placement with an approved supervisor before the course begins (a list of potential supervisors can be obtained from the Department of Pharmacology and Toxicology). Students will be registered in the course once their ballot form (obtained from the Department of Pharmacology and Toxicology) is signed by an approved supervisor and approved by the Department of Pharmacology and Toxicology. PCL473Y1 This is a survey course that explores past and contemporary problems in toxicology. The toxicities associated with a variety of toxins and toxicants are examined. General principles and the application of toxicological knowledge are emphasized. Several areas of medical toxicology, forensic toxicology, environmental toxicology and risk assessment are addressed. PCL474Y1 This course affords students an opportunity for hands-on research experience in a laboratory or applied toxicology setting. Students will work under the supervision of a staff member and will submit a final written report. Enrollment is limited and requires permission from the Department of Pharmacology and Toxicology. It is the student’s responsibility to secure a placement with an approved supervisor before the course begins (a list of potential supervisors can be obtained from the Department of Pharmacology and Toxicology). Students will be registered in the course once their ballot form (obtained from the Department of Pharmacology) is signed by an approved supervisor and approved by the Department of Pharmacology and Toxicology. PCL475Y1 Major neuro-psychiatric disease syndromes: clinical pathology and neuronal abnormalities; CNS drugs: theories and mechanisms of action. PCL477H1 Many anticancer drugs and environmental agents exert their cytotoxic effects through DNA damage. This course explores specific pharmacological and toxicological agents that damage DNA and discusses how mammalian cells respond to this DNA damage. PCL481H1 The biochemical principles and molecular mechanisms underlying the toxicity of drugs and foreign agents. The sequence of events at the molecular level leading to impairment of cell function and the factors which determine and affect toxicity. |