Physiology Courses

Key to Course Descriptions.

For Distribution Requirement purposes, all PSL courses are classified as SCIENCE courses.

| Course Winter Timetable |


PSL201Y1
Basic Human Physiology [52L]

A survey course intended for students who are not proceeding further in Physiology.
Exclusion: Any PSL course taken previously or concurrently
Prerequisite: 100-level course in BIO or equivalent


PSL280H1
Introduction to Physiologic Adaptations of Marine Mammals [24L, 12P]

Systems approach to physiology of marine mammals in their aquatic environment. Highlights unique features of cardiovascular, respiratory, gastrointestinal, renal, urinary, and reproductive systems. Introduces relevant nervous and endocrine physiology, and makes comparisons to human condition and disease.
Exclusion: EEB216H1
Prerequisite: BIO150Y1, CHM138H1


PSL299Y1
Research Opportunity Program

Credit course for supervised participation in faculty research project. Details here.


PSL300H1
Human Physiology I [36L, 5T]

Principles of neurophysiology, endocrinology and reproductive physiology for students enroled in the Neuroscience program.
Exclusion: PSL201Y1, PSY391H1
Prerequisite: BIO150Y1; CHM138H1; PHY100-series


PSL301H1
Human Physiology II [36L, 4T]

Principles of respiratory, cardiovascular, gastrointestinal, and renal physiology for students enroled in the Neuroscience program.
Exclusion: PSL201Y1
Prerequisite: BIO150Y1; CHM138H1; PSL300H1


JBO302Y1
Human Physiology and Biophysics [72L, 12T]

Principles of Human Physiology with tutorials on the biophysical concepts applied to physiological processes. Restricted to students enroled in the Biophysics program.
Exclusion: PSL201Y1, PSL302Y1
Prerequisite: BIO150Y1; CHM138H1; MAT135Y1/MAT137Y1; PHY138Y1/140Y1


PSL302Y1
Human Physiology [72L, 9T]

Principles of Human Physiology for students enroled in Basic Medical Science programs.
Exclusion: PSL201Y1
Prerequisite: BIO150Y1, CHM138H1; MAT100-series/PHY100-series


PSL303Y1
Topics in Cellular, Molecular and Organismic Physiology [72L, 24T]

Using homeostasis and feedback as a unifying theme, topics in control systems, cell signaling, rhythms, environmental adaptations and body weight regulations are examined. Tutorials use computer simulations and problem sets.
Prerequisite: JBO302Y1/PSL302Y1, MAT 100-series, PHY 100-series
Co-requisite: PSL372H1, PSL374H1 or permission of Department


PSL350H1
Mammalian Molecular Biology [20L, 6S]

Molecular biology is essential for understanding mammalian function. The knowledge from BIO250Y of DNA, RNA, and protein is extended to current, primary literature on mammalian molecular biology. Application of molecular biology to disease and to complex behaviors is followed by small group sessions on topics with a bioethics component.
Prerequisite: BIO250Y1
Exclusion: BCH311H1/BIO349H1/CSB349H1/MGY311Y1
Pre- or co-requisite: PSL300H1/PSL301H1/PSL302Y1/JBO302Y1, BCH210H1


PSL372H1
Mammalian Physiology Laboratory [12L, 36P]

A laboratory course covering selected topics in physiology.
Prerequisite: BIO250Y1, BCH210H1, MAT 100-series/PHY 100-series
Pre- or co-requisite: PSL302Y1, BCH370H1 (recommended)


PSL374H1
Advanced Physiology Laboratory [12L, 12S, 36P]

A problem-based laboratory course focused on the integration of organ systems to understand the control mechanisms of body function.
Prerequisite: BIO250Y1, PSL302Y1, PSL372H1
Co-requisite: BCH370H1


PSL378H1
Field Physiology: Marine Mammal [12L, 36P, 24T]

An opportunity to go outside of the traditional university classroom and get some hands on experience of the diversity and adaptive nature of marine mammalian physiology/anatomy as it compares to human. The course is 2 weeks (in May or June), one week in the field hands on, and one week of group discussions of the findings and draft report preparation.
Prerequisite: BIO252Y1/PSL201Y1/PSL280H1/PSL302Y1


PSL380H1
Physiologic Adaptations to Diving.[24L, 6T]

This course will compare and contrast the physiologic and anatomical adaptations exhibited by the different species of marine mammals in relationship to humans, with a focus on relevant aspects of diving.
Prerequisite: BIO252Y1/PSL201Y1/PSL302Y1, PSL280H1


PSL420H1
Reproduction I: Development and Function [24L]

This course provides an in-depth review of the development and function of the male and female reproductive systems. Topics include sex determination and differentiation, gametogenesis, hormonal control of the reproductive systems, the female ovulatory cycle, seasonal breeding, sexual behaviour, fertilization and implantation.
Prerequisite: PSL302Y1


PSL421H1
Reproduction II: Pregnancy and Birth [24L]

General overview of the integrated physiologic events associated with pregnancy and birth. The approach emphasizes physiologic processes using insights gained from studies of humans, animals, cells and genes. Where appropriate the clinical consequences of aberrant development are reviewed.
Prerequisite: PSL302Y1
Recommended Preparation: PSL420H1


PSL425H1
Integrative Metabolism and its Endocrine Regulation [24L]

This course integrates the newest findings and experimental approaches from cellular and molecular biology into metabolic function at the tissue, organ and whole body level.
Prerequisite: BCH210H1, PSL302Y1
Recommended Preparation: PSL303Y1


PSL432H1
Theoretical Physiology [24L]

Theoretical treatment of neurophysiology. Mathematical modeling and analysis of neurophysiological systems.
Prerequisite: MAT235Y1/MAT237Y1; APM346H1/MAT244H1
Recommended Preparation: PHY200-series; PSL201Y1/PSL302Y1/ BIO252Y1


PSL440Y1
Neuroscience I: Systems and Behaviour [72L]

Introduction to systems neuroscience. A review of basic neuroanatomy and physiology followed by in-depth study of selected sensory and motor systems. Students with an elementary neuroscience background progress to reading neuroscience literature on their own.
Prerequisite: PSL300H1/PSL302Y1/PSY290H1/CSB332H1 or equivalent


PSL443H1
Motor Control Systems [24L]

Control of body movement and posture by the nervous system in normal and pathological conditions. Topics include nonlinear dynamical systems, central pattern generators in the cerebral cortex, brainstem and spinal cord, reflexes, and basal ganglia-cerebellar function.
Prerequisite: PSL300H1/PSL302Y1


PSL444Y1
Neuroscience II: Cellular and Molecular [72L]

Overview of the fundamentals of cellular and molecular aspects of brain function. Course material is updated yearly to reflect the rapid evolution of ideas in Neuroscience.
Prerequisite: PSL300H1/PSL302Y1/CSB332H1


PSL450H1
Mechanisms of Neural and Endocrinal Secretion [24L]

Exocytosis and other aspects of secretion mainly in neurons and neuroendocrine cells, but also in pancreatic cells. Topics include synapse anatomy and physiology, synaptic plasma membrane and vesicle proteins, membrane fusion, genetic tools, endocrine secretion, plasticity in neurotransmitter release, diseases arising from secretion defects.
Prerequisite: BCH210H1, PSL302Y1/BIO252Y1, PSL350H1/CSB349H1


PSL452H1
Membrane Physiology [24L]

Biophysics and molecular biology of ion channels. Topics include equivalent circuits for cells, molecular structure of voltage-gated channels, distribution of channels, relationship between single-channel and whole-cell recording and regulation of channel function by voltage, phosphorylation, G-proteins and metabolites.
Prerequisite: PSL302Y1
Recommended Preparation: PSL432H1


PSL454H1
Physiological Instrumentation and Electronics [12L, 36P]

A practical approach to instrumentation as a preparation for using sophisticated measurement systems.
Prerequisite: PHY138Y1 or equivalent


PSL462H1
Molecular Aspects of Cardiovascular Function [24L]

Heart anatomy and development, ion channels and contractile proteins involved in cardiac and smooth muscle contraction are studied. Emphasis is on regulation of electrical and contractile function of kinases, metabolism, volume and ions.
Prerequisite: PSL302Y1/PSL303Y1


PSL470H1
Cardiovascular Physiology [24L, 12T]

Development of the cardiovascular system from conception to adulthood with particular emphasis on maturational changes, age-related differences and developmental problems from cellular/molecular to whole organ/system.
Prerequisite: PSL302Y1


PSL472H1
Sleep Physiology and Chronobiology [24L]

An in-depth analysis of the basic physiology underlying sleep and circadian rhythms, and of their impact on important physiological processes, of which effects on cardio-respiratory systems are emphasized.
Prerequisite: PSL302Y1


PSL498Y1
Project in Physiology [144P]

PSL499H1
Project in Physiology [72P]

Laboratory research project with reading assignments leading to a final report. By special arrangement with a Physiology staff member after admission to course. PSL498Y1 is recommended for students applying to the Physiology graduate program.
Prerequisite: PSL303Y1, PSL372H1, PSL374H1, permission of Department