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MBY Microbiology Courses NOTE: As of September 2000, the designator for Microbiology courses has been changed from MPL to MBY. MBY299Y
JZM357H1 Morphology, life cycles, evolutionary history and adaptations
to a parasitic mode of life. Host-parasite relationships are explored through the study of
various helminths and arthropod parasites, the diseases they cause, and our attempts to
control them. JZM358H1 Morphology, life cycles, evolutionary history and adaptations
to a parasitic mode of life. Host-parasite relationships are explored through the study of
various protozoan parasites, the diseases they cause, and our attempts to control them. MBY376H1 Fundamental laboratory techniques in bacteriology and
virology. Valuable not only for students specializing in Microbiology but also for those
in related disciplines which make use of bacteria and viruses as research tools. Open to
students in related programs. MBY377H1 Detailed study of bacteria in terms of structure,
classification and replication. Basis for advanced study in various aspects of
bacteriology including bacterial physiology, bacterial genetics, molecular pathogenesis of
disease and environmental studies.
Detailed study of viruses in terms of structure,
classification and replication. Basis for advanced study in virology. MBY422Y1 TBA MBY428H1 This course aims to explore and understand microbial genome
diversity and the evolutionary dynamic of microbial genomes. Topics include: structure and
diversity of microbial (eubacterial and archaebacterial) genomes; orientation and overall
organization of genes at the genomic level; mobile genetic elements; restriction and
modification systems; genome and codon evolution. MBY434H1 A survey of bacterial metabolism and its regulation from a
basic knowledge of bacterial physiology, biochemistry and molecular biology. Emphasis is
placed on mechanisms of sensing and adjusting to environmental stresses. Topics include:
carbon/energy/metabolism and catabolite repression; adjustments to aerobic/anaerobic
conditions, changes in osmolarity and starvation for amino acids, nitrogen and phosphate;
chemoreceptors, bioluminescence, and response to environmental stress, such as DNA damage
and heat shock. MBY440H1 Analysis of virus/host interactions at the molecular level.
Course material is based on recent research publications. MBY444H1 Microorganisms normally exist in mixed communities whose
composition and activity reflect the physical and chemical status of each particular
niche. The structural analysis, nutrient cycling, and dynamics of microbe-microbe
interactions in terrestrial, freshwater, and marine ecosystems are explored. The role of
microorganisms in bioremediation is examined. MBY445H1 Current approaches to gene therapy including design of
virus-based vectors for delivery and expression of effector genes. Emphasis on the use of
retrovirus-based strategies for prevention and treatment of HIV infection. MBY450H1 A laboratory course focussing on the use of molecular
techniques to study microorganisms and their interactions with the host. MBY480H1 Analysis of infectious disease vaccines; past, present and
future, with an emphasis on molecular aspects. Special topics include: molecular basis of
pathogenicity; vaccination strategies; genetically engineered vaccines; DNA vaccines;
modulation of the immune response by vaccine adjuvants; adverse effects of vaccines. |
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