2001/2002 Calendar
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CHM Chemistry Courses

| Course Winter Timetable |


SCI199Y1
First Year Seminar 52T

Undergraduate seminar that focuses on specific ideas, questions, phenomena or controversies, taught by a regular Faculty member deeply engaged in the discipline. Open only to newly admitted first year students. It may serve as a distribution requirement course; see page 44.
NOTE CHM138H and 139H may be taken in either order, and not in the same session.


CHM138H1
Chemistry: Structure and Reactivity 39L, 24P, 12T

An introduction to principles of structure and their relation to reactivity with an emphasis on the chemistry of organic molecules. Included are: atomic and molecular structure, stereochemistry, acid/base equilibria, functional groups, and fundamental reactions of organic molecules with a mechanistic emphasis. Recommended for students in life and health science programs.
Exclusion: CHM 151Y, 240Y
Prerequisite: OAC Chemistry, OAC Mathematics
Co-requisite: MAT135Y/137Y/157Y required; PHY110Y/138Y/140Y recommended


CHM139H1
Chemistry: Physical Principles 39L, 18P, 12T

Recommended for students in life and health science programs. Structure of matter, gases, liquids and solids; phase equilibria and phase diagrams; colligative properties; chemical equilibria; electrolyte solutions and electrochemistry; reaction kinetics; introduction to thermodynamics.
Exclusion: CHM 133H, 137Y, 151Y
Prerequisite:OAC Chemistry, OAC Mathematics
Co-requisite: MAT135Y/137Y/157Y required; PHY110Y/138Y/140Y recommended


CHM151Y1
Chemistry: The Molecular Science 78L, 35P, 26T

Strongly recommended for students interested in following specialist or major programs in Chemistry, and/or whose fields of study include a substantial amount of chemistry. The lecture course and lab provide an introduction to some of the exciting current areas of chemistry. Topics include: lasers and spectroscopy, organic molecules, biological and synthetic polymers, and materials with novel properties such as superconductors.
Note: Students taking Chemistry and Physics may schedule the labs on the same afternoon of alternate weeks.
Exclusion: CHM137Y, (132H, 133H), (138H, 139H)
Prerequisite: OAC Chemistry + OAC Mathematics (Calc, A&G); OAC Physics recommended
Co-requisite: MAT135Y/137Y/157Y; PHY110Y/138Y/140Y


CHM200Y1
The Role of Chemistry in Modern Society 52L

Human beings are constructed physically of chemicals, live in a sea of chemicals and are very dependent for their material quality of life on the modern chemical industry. This course is especially for non-science students who wish to develop a better understanding of the impact and importance of chemistry in industry, society and the environment. The course should be of particular interest to students with interests in economics, commerce, management, politics, psychology and teaching.
Exclusion: Students who have taken one or more university-level courses in chemistry require permission of the instructor.
Prerequisite: completion of 5 full courses at the university level


CHM217H1
Introduction to Analytical Chemistry 26L, 52P, 13T

Introduction to classical and instrumental analytical chemistry. Scope of analytical chemistry: statistical methods; signal response, sensitivity and limit-of-detection of various techniques. Solution equilibrium applications: gravimetry, titrimetry, acid-base, redox and complexometric processes. Absorption spectroscopy: Beer's Law.
Prerequisite: CHM137Y/(132H, 133H)/(138H, 139H)/151Y


CHM220H1
Physical Chemistry for Life Sciences 39L, 13T

Introduction to thermodynamics; phase equilibrium, chemicals equilibrium, electrochemistry; introduction to quantum mechanics and spectroscopy.
Exclusion: CHM222Y, 225Y
Prerequisite: CHM(138H, 139H)/151Y; MAT135Y/137Y/157Y
Recommended co-requisite: MAT235Y


CHM221H1
Physical Chemistry: The Molecular Viewpoint 26L, 13T

Intended as a continuation of CHM220H for students wishing to take some additional material in Physical Chemistry. The course covers topics in quantum mechanics and spectroscopy as well as an introduction to reaction kinetics.
Exclusion:tCHM222Y, 225Y
Prerequisite: CHM220H and permission of the department
Recommended co-requisite: MAT235Y/237Y


CHM225Y1
Introduction to Physical Chemistry 52L, 26T

Directed to students in the Chemistry major and specialist programs. Topics: introductory thermodynamics, first and second law and applications; chemical equilibrium; electrochemistry, surface chemistry; chemical kinetics; introductory quantum mechanics; spectroscopy, and molecular photophysics.
Exclusion: CHM222Y, 220H, 221H
Prerequisite: CHM137Y/(132H, 133H)/(138H, 139H)/151Y, MAT135Y/137Y/157Y, PHY110Y/138Y/140Y
Recommended co-requisite: MAT235Y/237Y


ENV235Y1
Physics and Chemistry of Planet Earth

(see "ENV: Division of the Environment")


CHM238Y1
Introduction to Inorganic Chemistry 52L, 52P

The first part (with CHM338H) of a two-year sequence in Inorganic Chemistry, designed to illustrate and systematize the rich variety of structures, physical properties and reactions of compounds of the elements across and down the Periodic Table. Introduction to structure, symmetry and bonding of molecules and lattices; acid-base and redox reactions; d-metal complexes; systematic chemistry of metals and elements of the s and p blocks; inorganic materials and solid state chemistry with applications in advanced technologies. The laboratory runs weekly from January to April.
Prerequisite: CHM151Y/137Y/(132H, 133H)/(138H, 139H)


CHM247H1
Introductory Organic Chemistry 39L, 26P

The fundamentals of organic chemistry with a focus on major reactions of organic compounds.Included are principles of mechanism, synthesis, and spectroscopy.
Exclusion: CHM240Y, 248Y
Prerequisite: CHM(138H, 139H)/151Y


CHM248Y1
Organic Chemistry I 52L, 52P

An in-depth survey of organic molecules and principles of their reactions. Emphasis is on understanding of the basics with respect to structure and bonding, and application of reactions to the synthesis of medicinally and industrially important compounds. Continues from CHM 151Y.
Exclusion: CHM240Y, 247H
Prerequisite: CHM(138H, 139H)/151Y/(137Y/(132H, 133H) with permission)


CHM299Y1
Research Opportunity Program


Credit course for supervised participation in faculty research project. See page 44 for details.


CHM310H
Environmental Chemistry 26L

Major chemical pollutants and their sources, the environmental reactions they undergo, and how they become distributed throughout the environment. Focus is on the principal routes of chemical and biological degradation of toxicants; oxidation, photodegradation, hydrolysis, reduction, biotic metabolism, and microbial degradation. The principal physical processes by which chemicals move, concentrate, and dissipate.
Prerequisite: CHM240Y/247H/248Y


CHM314Y1
Introduction to Instrumental Methods of Analysis 52L, 52P

Scope of instrumental analytical chemistry; Fourier transform IR absorption spectroscopy; molecular luminescence; emission spectroscopy; mass spectroscopy, electrochemical techniques; sensors; gas and high performance liquid chromatography; instrument design principles and applications in industry and the environment. The laboratory runs weekly from January to April.
Prerequisite: CHM217H
Recommended preparation: CHM222Y/225Y


CHM325H1
Materials Chemistry 26L

Fashioned to illustrate how inorganic and polymer materials chemistry can be rationally used to synthesize superconductors, metals, semiconductors, ceramics, elastomers, thermoplastics, thermosets and polymer liquid crystals, with properties that can be tailored for applications in a range of advanced technologies. Coverage is fairly broad and is organized to crosscut many aspects of the field.
Prerequisite: CHM220H/222Y/225Y, 238Y, 240Y/247H/248Y


CHM326H1
Introductory Quantum Mechanics and Spectroscopy 26L, 26P

This course introduces the postulates of quantum mechanics to develop the fundamental framework of quantum theory. A number of exactly soluble problems are treated in detail as examples. Perturbation theory is introduced in the context of understanding many body problems. Various applications to molecular spectroscopy and dynamics are covered in detail.
Prerequisite: CHM225Y (or CHM220H/222Y with permission of instructor), MAT235Y/237Y


CHM328H1
Modern Physical Chemistry 26L, 26P

This course explores the microscopic description of macroscopic phenomena in chemistry. Statistical mechanics is introduced as the bridge between the microscopic and macroscopic views, and applied to a variety of chemical problems including reaction dynamics. More advanced topics in thermodynamics are introduced and discussed as required.
Prerequisite: CHM225Y (or CHM220H/222Ywith permission of instructor), MAT235Y/237Y


CHM338H1
Intermediate Inorganic Chemistry 26L, 52P

Further study of the structures, physical properties and reactions of compounds of the elements with emphasis on the transition metals. Introductions to spectroscopy and structural analysis, reaction mechanisms, d- and f- block organometallic compounds, catalysis, structures of solids and bioinorganic chemistry. The weekly laboratory demonstrates aspects of transition metal chemistry.
Prerequisite: CHM238Y
Recommended Preparation: CHM217H, 240Y/247H/248Y


CHM345H1
Modern Organic Synthesis 26L

An overview of the preparation of various classes of organic compounds. Strategies and tactics of synthetic organic chemistry using examples from natural product and drug syntheses. C-C bond formation, functional group reactivity, structure, stereochemistry and selectivity. (This course is not allowed for students in any of the Chemistry specialist and major programs; they should consider CHM346H instead.)
Exclusion: CHM346H
Prerequisite: (CHM240Y/247H with permission of Department)/248Y


CHM346H1
Modern Organic Synthesis 26L, 52P

An overview of the preparation of various classes of organic compounds. Strategies and tactics of synthetic organic chemistry using examples from natural product and drug syntheses. C-C bond formation, functional group reactivity, structure, stereochemistry and selectivity. (Students who are not in one of the Chemistry specialist and major programs should consider taking CHM345H instead of this course.)
Exclusion: CHM345H
Prerequisite: CHM248Y


CHM347H1
Organic Chemistry of Biological Compounds 26L

Structure, reactions, and preparation of metabolically important compounds based on modern concepts of organic chemistry. Advanced stereochemistry, carbohydrate structure and reactivity, amino acid and peptide synthesis, reactions of nitrogen heterocycles, synthesis and analysis of nucleotide and phosphate esters, synthesis of drugs.
Prerequisite: CHM240Y/247H/248Y


CHM348H1
Organic Reaction Mechanisms 26L, 26P

Analysis of structure and reactions of organic molecules in terms of physical principles. Mechanistic principles of important classes of organic reactions.
Prerequisite: CHM240Y/247H/248Y


CHM379H1
Biomolecular Chemistry 26L, 24P

Biological macromolecules; structure, function and catalysis in the context of biological phenomena. This course extends principles learned in earlier chemistry courses to the understanding of important biochemical phenomena.
Exclusion: BCH210H, 242Y, 310H, 321Y
Prerequisite: CHM240Y/247H/248Y, 347H
Recommended preparation: CHM348H


CHM398H0/399Y0
Independent Experiential Study Project


An instructor-supervised group project in an off-campus setting. See page 44 for details.


CHM410H1
Analytical Environmental Chemistry 26L, 32P

An analytical theory, instrumental, and methodology course focused on the measurement of pollutants in soil, water, air, and biological tissues and the determination of physical/chemical properties including vapour pressure, degradation rates, partitioning.
Lab experiments involve application of theory.
Prerequisite: CHM310H
Recommended preparation: CHM314Y


CHM414H1
Developing Techniques in Analytical Chemistry 26L

Current research in analytical chemistry with emphasis on rapidly emerging techniques. Course topics chosen from biosensor technology, transducer theory and operation, device design and fabrication, surface modification and methods of surface analysis, flow injection analysis and chemometrics.
Recommended preparation: CHM314Y


CHM415H1
Atmospheric Chemistry 26L

This course considers the chemistry occuring in the Earth's atmosphere, with emphasis on developing molecular-level understanding of the photochemistry, free-radical kinetics, and heterogeneous chemistry that occurs. Topics include stratospheric ozone depletioon, trace gas oxidation, urban air pollution, acid rain, and the connections between aerosols and climate.
Prerequisite: CHM220H/225Y/310H
Recommended preparation: MAT135Y/137Y; PHY138Y/140Y


CHM416H1
Separation Science 26L

Principles of separation in analytical chemistry. Fractionation processes and solvent extractions; theory of chromatography, retention time, column efficiency and resolution. Principles of gas-liquid chromatography; instrumentation for gas chromatography. High performance liquid chromatography - practice and equipment design. Ion exchange, size-exclusion and affinity chromatography. Electrophoretic techniques.
Prerequisite: CHM314Y


CHM418Y1
Introduction to Research in Analytical Chemistry 260P

An experimental or theoretical research problem under the supervision of a member of staff. Applications for enrolment should be made to the Department in the preceding Winter Session.
Exclusion: CHM428Y/439Y/449Y
Prerequisite: Permission of Department
Recommended preparation: CHM314Y


CHM421H1
Chemical Kinetics and Dynamics 26L

Reaction mechanisms; collision dynamics; theory of the rates of elementary processes; introduction to complex reactions including nonlinear processes.
Prerequisite: CHM(326H, 328H)


CHM423H1
Applications of Quantum Mechanics 26L

Applications of time independent and time dependent perturbation theory to atomic and molecular problems; WKB approximation and the classical limit; the interaction of light with matter; elementary atomic scattering theory.
Prerequisite: CHM326H


CHM426H1
Polymer Chemistry 26L

Scope of polymer chemistry. Organic and inorganic polymers. Synthesis and characterization of polymers. Polymers as advanced materials. Polymers in solution: Flory-Huggins theory. Polymers in the solid state: crystalline and amorphous polymers, the effects of the glass transition on polymer properties.
Prerequisite: CHM325H; two of CHM328H, 338H, 348H or permission of the instructor


CHM427H1
Statistical Mechanics 26L

Ensemble theory in statistical mechanics. Applications, including imperfect gases and liquid theories. Introduction to non-equilibrium problems.
Prerequisite: CHM(326H, 328H)


CHM428Y1
Introduction to Research in Physical Chemistry 260P

An experimental or theoretical research problem under the supervision of a member of the Physical Chemistry staff. Enrolment in this course may be restricted and must be approved by the Department. Applications for enrolment should be made to the Department in the preceding Winter Session.
Exclusion: CHM418Y/439Y/449Y
Prerequisite: CHM326H/328H and permission of Department


CHM432H1
Organometallic Chemistry 26L

Structure, bonding, and reactions of organometallic compounds, with emphasis on basic mechanisms, and industrial processes. Addition, metalation, substitution, elimination, important catalytic cycles, electrophilic, and nucleophilic reactions are considered on a mechanistic basis. Properties of s and p block organometallics.
Prerequisite: CHM338H
Recommended preparation: CHM348H


CHM434H1
Solid State Chemistry 26L

The development of newer methods of synthesizing primarily inorganic solids, growing crystals and depositing films that have properties tailored for particular uses. The subject matter covers materials chemistry aspects of host-guest inclusion, self-assembling frameworks, synthetic electrical conductors, nanochemistry, buckyballs, buckytubes, biomineralization and biomimetics. The interrelationship to property and function is critically examined and how these create opportunities for new materials applications and technologies.
Prerequisite: CHM325H, 338H


CHM437H1
Bio-Inorganic Chemistry 26L

Essential elements in biology; naturally occurring and medicinal ligands; transport, uptake and control of concentration of metal ions; physical methods of characterization of metal binding sites. Roles of metal ions: as structural and signaling elements in proteins, nucleic acids and DNA-binding complexes and proteins; as Lewis-acid centres in enzymes; as carriers of electrons, atoms and groups in redox proteins and enzymes; as sources of biominerals; as radiopharmaceuticals.
new.gif (103 bytes) Prerequisite: CHM238Y
Recommended preparation: CHM 338H, CHM347H/379H


CHM438H1
Advanced Inorganic Chemistry Laboratory 130P

A four-week intensive laboratory course during the first half of the Fall Session. Eight set experiments designed to illustrate one or more facets of synthetic, spectroscopic and analytical studies in inorganic chemistry. Applications for enrolment should be made to the Department in the preceding Winter Session.
Prerequisite
: CHM338H and permission of Department


CHM439Y1
Introduction to Research in Inorganic Chemistry 260P

An experimental or theoretical research problem under the supervision of a staff member. Applications for enrolment should be made to the Department in the preceding Winter Session.
Exclusion: CHM418Y/428Y/449Y
Prerequisite: Permission of Department
Co-requisite: CHM438H


CHM440H1
The Synthesis of Modern Pharmaceutical Agents 26L

Overview of classes of molecules currently used in treatment of diseases. Within each therapeutic area, representative drugs on the market are considered and their syntheses discussed. Reactions taught in previous courses and new reactions are used. Students also gain appreciation of the mode of action, discovery and development of drugs in the pharmaceutical industry today.
Prerequisite: CHM345H/346H


CHM441H1
Spectroscopic Analysis in Organic Chemistry 13L, 6P, 13T

Structure and stereochemistry determination using modern spectroscopic techniques. The main focus of the course is on NMR spectroscopy (1H and 13C). Other spectroscopy techniques are discussed briefly, including infrared, X-ray and mass spectral methods. The approach taken emphasizes applications of these spectroscopic methods to organic problems.
Prerequisite: CHM345H/346H/348H


CHM443H1
Physical Organic Chemistry 26L

Methods for the determination of organic reaction mechanisms. Computational calculations; kinetic techniques; study of reaction intermediates; structure-reactivity correlations; linear free energy relationships; medium effects; isotope effects; acid-base catalysis.
Prerequisite: CHM220H/222Y/225Y, 348H


CHM447H1
Bio-organic Chemistry 26L

Applications of organic chemistry and physical organic chemistry to the study of biologically important processes. Kinetics and mechanisms of enzyme catalysis, chemistry of co-enzymes, stereochemistry of biological reactions, biosynthesis of important biological molecules.
Prerequisite: BCH321Y/(CHM379H, 347H)
Recommended preparation: CHM348H


CHM449Y1
Introduction to Research in Organic Chemistry 260P

An experimental research problem under the supervision of a faculty member. Applications for enrolment should be made to the Department in the preceding Winter Session. Projects in the areas of synthetic, physical and bio-organic chemistry are offered.
Exclusion: CHM418Y/428Y/439Y
Prerequisite: Permission of Department
Recommended preparation: CHM346H/348H/379H


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