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CHM Chemistry Courses SCI199Y1 Undergraduate seminar that focuses on specific ideas,
questions, phenomena or controversies, taught by a regular Faculty member deeply engaged
in the discipline. Open only to newly admitted first year students. It may serve as a
distribution requirement course; see page 44. CHM138H1 An introduction to principles of structure and their relation
to reactivity with an emphasis on the chemistry of organic molecules. Included are: atomic
and molecular structure, stereochemistry, acid/base equilibria, functional groups, and
fundamental reactions of organic molecules with a mechanistic emphasis. Recommended for
students in life and health science programs. CHM139H1 Recommended for students in life and health science programs.
Structure of matter, gases, liquids and solids; phase equilibria and phase diagrams;
colligative properties; chemical equilibria; electrolyte solutions and electrochemistry;
reaction kinetics; introduction to thermodynamics. CHM151Y1 Strongly recommended for students interested in following
specialist or major programs in Chemistry, and/or whose fields of study include a
substantial amount of chemistry. The lecture course and lab provide an introduction to
some of the exciting current areas of chemistry. Topics include: lasers and spectroscopy,
organic molecules, biological and synthetic polymers, and materials with novel properties
such as superconductors. CHM200Y1 Human beings are constructed physically of chemicals, live in
a sea of chemicals and are very dependent for their material quality of life on the modern
chemical industry. This course is especially for non-science students who wish to develop
a better understanding of the impact and importance of chemistry in industry, society and
the environment. The course should be of particular interest to students with interests in
economics, commerce, management, politics, psychology and teaching. CHM217H1 Introduction to classical and instrumental analytical
chemistry. Scope of analytical chemistry: statistical methods; signal response,
sensitivity and limit-of-detection of various techniques. Solution equilibrium
applications: gravimetry, titrimetry, acid-base, redox and complexometric processes.
Absorption spectroscopy: Beer's Law. CHM220H1 Introduction to thermodynamics; phase equilibrium, chemicals
equilibrium, electrochemistry; introduction to quantum mechanics and spectroscopy. CHM221H1 Intended as a continuation of CHM220H
for students wishing to take some additional material in Physical Chemistry. The course
covers topics in quantum mechanics and spectroscopy as well as an introduction to reaction
kinetics. CHM225Y1 Directed to students in the Chemistry major and specialist
programs. Topics: introductory thermodynamics, first and second law and applications;
chemical equilibrium; electrochemistry, surface chemistry; chemical kinetics; introductory
quantum mechanics; spectroscopy, and molecular photophysics. ENV235Y1 (see "ENV: Division of the Environment") CHM238Y1 The first part (with CHM338H)
of a two-year sequence in Inorganic Chemistry, designed to illustrate and systematize the
rich variety of structures, physical properties and reactions of compounds of the elements
across and down the Periodic Table. Introduction to structure, symmetry and bonding of
molecules and lattices; acid-base and redox reactions; d-metal complexes; systematic
chemistry of metals and elements of the s and p blocks; inorganic materials and solid
state chemistry with applications in advanced technologies. The laboratory runs weekly
from January to April. CHM247H1 The fundamentals of organic chemistry with a focus on major
reactions of organic compounds.Included are principles of mechanism, synthesis, and
spectroscopy. CHM248Y1 An in-depth survey of organic molecules and principles of
their reactions. Emphasis is on understanding of the basics with respect to structure and
bonding, and application of reactions to the synthesis of medicinally and industrially
important compounds. Continues from CHM 151Y. CHM299Y1
CHM310H Major chemical pollutants and their sources, the
environmental reactions they undergo, and how they become distributed throughout the
environment. Focus is on the principal routes of chemical and biological degradation of
toxicants; oxidation, photodegradation, hydrolysis, reduction, biotic metabolism, and
microbial degradation. The principal physical processes by which chemicals move,
concentrate, and dissipate. CHM314Y1 Scope of instrumental analytical chemistry; Fourier transform
IR absorption spectroscopy; molecular luminescence; emission spectroscopy; mass
spectroscopy, electrochemical techniques; sensors; gas and high performance liquid
chromatography; instrument design principles and applications in industry and the
environment. The laboratory runs weekly from January to April. CHM325H1 Fashioned to illustrate how inorganic and polymer materials
chemistry can be rationally used to synthesize superconductors, metals, semiconductors,
ceramics, elastomers, thermoplastics, thermosets and polymer liquid crystals, with
properties that can be tailored for applications in a range of advanced technologies.
Coverage is fairly broad and is organized to crosscut many aspects of the field. CHM326H1 This course introduces the postulates of quantum mechanics to
develop the fundamental framework of quantum theory. A number of exactly soluble problems
are treated in detail as examples. Perturbation theory is introduced in the context of
understanding many body problems. Various applications to molecular spectroscopy and
dynamics are covered in detail. CHM328H1 This course explores the microscopic description of
macroscopic phenomena in chemistry. Statistical mechanics is introduced as the bridge
between the microscopic and macroscopic views, and applied to a variety of chemical
problems including reaction dynamics. More advanced topics in thermodynamics are
introduced and discussed as required. CHM338H1 Further study of the structures, physical properties and
reactions of compounds of the elements with emphasis on the transition metals.
Introductions to spectroscopy and structural analysis, reaction mechanisms, d- and f-
block organometallic compounds, catalysis, structures of solids and bioinorganic
chemistry. The weekly laboratory demonstrates aspects of transition metal chemistry. CHM345H1 An overview of the preparation of various classes of organic
compounds. Strategies and tactics of synthetic organic chemistry using examples from
natural product and drug syntheses. C-C bond formation, functional group reactivity,
structure, stereochemistry and selectivity. (This course is not allowed for students in
any of the Chemistry specialist and major programs; they should consider CHM346H instead.) CHM346H1 An overview of the preparation of various classes of organic
compounds. Strategies and tactics of synthetic organic chemistry using examples from
natural product and drug syntheses. C-C bond formation, functional group reactivity,
structure, stereochemistry and selectivity. (Students who are not in one of the Chemistry
specialist and major programs should consider taking CHM345H
instead of this course.) CHM347H1 Structure, reactions, and preparation of metabolically
important compounds based on modern concepts of organic chemistry. Advanced
stereochemistry, carbohydrate structure and reactivity, amino acid and peptide synthesis,
reactions of nitrogen heterocycles, synthesis and analysis of nucleotide and phosphate
esters, synthesis of drugs. CHM348H1 Analysis of structure and reactions of organic molecules in
terms of physical principles. Mechanistic principles of important classes of organic
reactions. CHM379H1 Biological macromolecules; structure, function and catalysis
in the context of biological phenomena. This course extends principles learned in earlier
chemistry courses to the understanding of important biochemical phenomena. CHM398H0/399Y0
CHM410H1 An analytical theory, instrumental, and methodology course
focused on the measurement of pollutants in soil, water, air, and biological tissues and
the determination of physical/chemical properties including vapour pressure, degradation
rates, partitioning. CHM414H1 Current research in analytical chemistry with emphasis on
rapidly emerging techniques. Course topics chosen from biosensor technology, transducer
theory and operation, device design and fabrication, surface modification and methods of
surface analysis, flow injection analysis and chemometrics. CHM415H1 This course considers the chemistry occuring in the Earth's
atmosphere, with emphasis on developing molecular-level understanding of the
photochemistry, free-radical kinetics, and heterogeneous chemistry that occurs. Topics
include stratospheric ozone depletioon, trace gas oxidation, urban air pollution, acid
rain, and the connections between aerosols and climate. CHM416H1 Principles of separation in analytical chemistry.
Fractionation processes and solvent extractions; theory of chromatography, retention time,
column efficiency and resolution. Principles of gas-liquid chromatography; instrumentation
for gas chromatography. High performance liquid chromatography - practice and equipment
design. Ion exchange, size-exclusion and affinity chromatography. Electrophoretic
techniques. CHM418Y1 An experimental or theoretical research problem under the
supervision of a member of staff. Applications for enrolment should be made to the
Department in the preceding Winter Session. CHM421H1 Reaction mechanisms; collision dynamics; theory of the rates
of elementary processes; introduction to complex reactions including nonlinear processes. CHM423H1 Applications of time independent and time dependent
perturbation theory to atomic and molecular problems; WKB approximation and the classical
limit; the interaction of light with matter; elementary atomic scattering theory. CHM426H1 Scope of polymer chemistry. Organic and inorganic polymers.
Synthesis and characterization of polymers. Polymers as advanced materials. Polymers in
solution: Flory-Huggins theory. Polymers in the solid state: crystalline and amorphous
polymers, the effects of the glass transition on polymer properties. CHM427H1 Ensemble theory in statistical mechanics. Applications,
including imperfect gases and liquid theories. Introduction to non-equilibrium problems. CHM428Y1 An experimental or theoretical research problem under the
supervision of a member of the Physical Chemistry staff. Enrolment in this course may be
restricted and must be approved by the Department. Applications for enrolment should be
made to the Department in the preceding Winter Session. CHM432H1 Structure, bonding, and reactions of organometallic
compounds, with emphasis on basic mechanisms, and industrial processes. Addition,
metalation, substitution, elimination, important catalytic cycles, electrophilic, and
nucleophilic reactions are considered on a mechanistic basis. Properties of s and p block
organometallics. CHM434H1 The development of newer methods of synthesizing primarily
inorganic solids, growing crystals and depositing films that have properties tailored for
particular uses. The subject matter covers materials chemistry aspects of host-guest
inclusion, self-assembling frameworks, synthetic electrical conductors, nanochemistry,
buckyballs, buckytubes, biomineralization and biomimetics. The interrelationship to
property and function is critically examined and how these create opportunities for new
materials applications and technologies. CHM437H1 Essential elements in biology; naturally occurring and
medicinal ligands; transport, uptake and control of concentration of metal ions; physical
methods of characterization of metal binding sites. Roles of metal ions: as structural and
signaling elements in proteins, nucleic acids and DNA-binding complexes and proteins; as
Lewis-acid centres in enzymes; as carriers of electrons, atoms and groups in redox
proteins and enzymes; as sources of biominerals; as radiopharmaceuticals. CHM438H1 A four-week intensive laboratory course during the first half
of the Fall Session. Eight set experiments designed to illustrate one or more facets of
synthetic, spectroscopic and analytical studies in inorganic chemistry. Applications for
enrolment should be made to the Department in the preceding Winter Session. CHM439Y1 An experimental or theoretical research problem under the
supervision of a staff member. Applications for enrolment should be made to the Department
in the preceding Winter Session. CHM440H1 Overview of classes of molecules currently used in treatment
of diseases. Within each therapeutic area, representative drugs on the market are
considered and their syntheses discussed. Reactions taught in previous courses and new
reactions are used. Students also gain appreciation of the mode of action, discovery and
development of drugs in the pharmaceutical industry today. CHM441H1 Structure and stereochemistry determination using modern
spectroscopic techniques. The main focus of the course is on NMR spectroscopy (1H and
13C). Other spectroscopy techniques are discussed briefly, including infrared, X-ray and
mass spectral methods. The approach taken emphasizes applications of these spectroscopic
methods to organic problems. CHM443H1 Methods for the determination of organic reaction mechanisms.
Computational calculations; kinetic techniques; study of reaction intermediates;
structure-reactivity correlations; linear free energy relationships; medium effects;
isotope effects; acid-base catalysis. CHM447H1 Applications of organic chemistry and physical organic
chemistry to the study of biologically important processes. Kinetics and mechanisms of
enzyme catalysis, chemistry of co-enzymes, stereochemistry of biological reactions,
biosynthesis of important biological molecules. CHM449Y1 An experimental research problem under the supervision of a
faculty member. Applications for enrolment should be made to the Department in the
preceding Winter Session. Projects in the areas of synthetic, physical and bio-organic
chemistry are offered. |
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