Pharmaceutical Chemistry Courses

Key to Course Descriptions

For Distribution Requirement purposes, all PHC courses are classified as SCIENCE courses except for PHC470H1, which is a SOCIAL SCIENCE course.

| Course Winter Timetable |


PHC300Y1
Molecular Pharmacology        78L, 26T

The molecular basis for the action of drugs is presented based upon the physicochemical nature of the drug and its target.
Prerequisite: CHM247H1/CHM249H1; (CHM220H1,CHM221H1)/CHM225Y1; BCH210H1


PHC320H1
Medicinal Chemistry        39 L

Modern discovery and synthesis of antibiotics, antineoplastics, antiviral and other therapeutic agents.
Prerequisite: CHM247H1/CHM249H1; BCH210H1


PHC330Y1
Pharmaceutics        78L, 24T

The study of the science and technology underlying drug delivery are covered. The properties of different dosage forms and delivery routes are studied with an emphasis on oral and parenteral routes.
Prerequisite: CHM247H1/CHM249H1; (CHM220H1,CHM221H1)/CHM225Y1; BCH210H1


PHC331H1
Establishing the Bioequivalence of Pharmaceutical Products 32L

Introduction to human clinical trial design for the demonstration of pharmaceutical bioequivalence of drug products. Students learn the principles underlying the regulations and methods employed in bioequivalence studies.
Prerequisite: MAT135Y1, BCH210H1, CHM247H1/249H1
Pre- or co-requisite: PHC330Y1/PHM224Y


PHC340Y1
Pharmaceutical Chemistry Laboratory       26L, 78P

The scientific basis and practical techniques relevant to modern pharmaceutical development.
Prerequisite: CHM247H1/CHM249H1; (CHM220H1,CHM221H1)/CHM225Y1; BCH210H1


PHC401H1
Drug Transport across Biological Membranes 26L

The goal of this course is to provide students with knowledge of the molecular processes involved in drug transport across biological cell membranes with emphasis on their physiological and clinical significance.
Prerequisite: PHC300Y1, Permission of the Department


PHC430H1
Recent Developments in Dosage Form Design       26L

Introduction to controlled drug delivery: Mechanisms and kinetics of controlled drug release. Fundamental theories and mathematical tools for the design of modern dosage forms. Development and applications of controlled drug delivery dosage forms.
Recommended: (PHC330Y1,PHC340Y1)/PHM224Y1, Permission of the Department


PHC431H1
Selected Topics in Drug Development       26L

In-depth discussion of implementation of pharmaceutical sciences in drug development strategies. Students will apply fundamental principles of pharmaceutics and drug delivery to current problems in the pharmaceutical industry.
Recommended: (PHC330Y1,PHC340Y1)/PHM224Y1, Permission of the Department


PHC450H1
Applications of Pharmaceutical Analysis in Pharmacy and Medicine        21L, 16P

Overview of methods of pharmaceutical analysis such as titrations, UV-visible, IR, NMR and mass spectroscopy, fluorescence, HPLC, GC, TLC, electrophoresis, blotting, immunoassays and radiometric methods. Regulatory aspects of drug product quality control are covered. Introduces applications in pharmacy, therapeutic drug monitoring, toxicology, forensic science, athletics and clinical laboratory medicine.
Prerequisites: PHC300Y1/PHM222Y, (PHC330Y1,PHC340Y1)/PHM224Y, Permission of the Department


PHC451H1
Radiopharmaceuticals in Diagnosis and Therapy        14L, 14P

Presents use of radiopharmaceuticals in diagnosis and therapy, emphasizing those used in nuclear medicine procedures studying neurological, cardiovascular, pulmonary, gastrointestinal, haematologic, endocrine and bone pathology.
Prerequisite: (PHC330Y1,PHC340Y1)/PHM 224Y1, Permission of the Department


PHC452H1
Selected Topics in Radiopharmaceuticals        14L, 12P

Introduces nuclear pharmacy through the discussion of problems that explain the design, production, analysis, and the clinical use of radiopharmaceuticals. Topics introduced using group discussions and laboratory exercises.
Prerequisites: (PHC330Y1,PHC340Y1)/PHM224Y, Permission of the Department


PHC460H1
Fundamentals of Drug Discovery        26L

Lectures by scientists from academia and industry, and student seminars based on journal articles dealing with strategies for discovering new drugs for therapy and diagnosis.
Prerequisites: BIO250Y1, PHC300Y1/PHM222Y1, Permission of the Instructor


PHC461H1
Selected Topics in the Pharmaceutical Industry        26L

Introduces drug development from the perspective of the pharmaceutical industry. Describes key stages in drug development process; current issues facing industry and role of pharmacists and pharmaceutical scientists in the process. Lectures are given by specialists employed in the pharmaceutical industry and concepts covered in the lectures will be applied to in-class case studies.
Prerequisites : PHC300Y1/PHM222Y1, (PHC330Y1,PHC340Y1)/PHM224Y1, Permission of the Department


PHC470H1
Global Pharmaceutical Policy: Power and Politics        26L

Introduces concepts and issues in international pharmaceutical policy. Emphasis placed on how governments in different jurisdictions manage their public health responsibilities, international obligations, and pressure from special interest groups in terms of pharmaceutical policy.
Prerequisite: Permission of the Department
This is a Social Science course.


PHC489Y1
Pharmaceutical Chemistry Research       156P

This course will provide research experience under the supervision of a Departmental staff member. The goal is to deepen the student’s understanding of the scientific basis and practical techniques relevant to modern pharmaceutical development.
Prerequisite: Permission of the Department and the Project Supervisor