2003/2004 Calendar
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MBY Microbiology Courses

| Course Winter Timetable |


MBY299Y1
Research Opportunity Program

Credit course for supervised participation in faculty research project. See page 40 for details.


MBY376H1
Microbiology Laboratory 78P

Fundamental laboratory techniques in bacteriology and virology. Valuable not only for students specializing in Microbiology but also for those in related disciplines which make use of bacteria and viruses as research tools. Open to students in related programs.
Prerequisite: BIO250Y1
Co-requisite: MBY377H1, 378H1
Recommended preparation: BIO 260H1/HMB 265H1


MBY377H1
Microbiology I: Bacteria 39L (formerly MBY375Y1)

Detailed study of bacteria in terms of structure, classification and replication. Basis for advanced study in various aspects of bacteriology including bacterial physiology, bacterial genetics, molecular pathogenesis of disease and environmental studies.
Prerequisite: BCH210H1/242Y1/310H1/321Y1; BIO250Y1


MBY378H1
Microbiology II: Viruses 39L (formerly MBY375Y1)

Detailed study of viruses in terms of structure, classification, replication and interaction with the host. Basis for advanced study in virology. Requires some familiarity with immunology. A concurrent course in immunology (IMM 334Y1/335Y1) is recommended.
Exclusion: BIO351Y1, MBY375Y1
Prerequisite: BCH210H1/242Y1/310H1/321Y1; BIO250Y1; BIO 260H1/HMB 265H1
Co-requisite: BIO349H1/MGB311Y1
Recommended preparation: MBY377H1


MBY422Y1
Research Project in Microbiology TBA

Under the supervision of a departmental staff member. (Open only to students who have completed Third Year with at least ‘B+’ standing)
Prerequisite: Permission of course coordinator


MBY428H1
Microbial Genomics 26L

This course aims to explore and understand microbial genome diversity and the evolutionary dynamic of microbial genomes. Topics include: structure and diversity of microbial (eubacterial and archaebacterial) genomes; orientation and overall organization of genes at the genomic level; mobile genetic elements; restriction and modification systems; genome and codon evolution.
Prerequisite: BCH210H1/242Y1/310H1/321Y1; MBY377H1


MBY434H1
Bacterial Signalling and Physiological Regulation 39L

How bacteria sense their environment and signal to regulatory systems when to adapt to environmental stimuli. Topics discussed include the bacterial cell cycle, carbon/energy metabolism, catabolite repression, bacterial development, sporulation, stress responses, regulatory two-component systems and quorum sensing.
Prerequisite: BCH210H1/242Y1/310H1/321Y1,MBY377H1, BIO349H1/MGB311Y1


MBY440H1
Molecular Virology 39L

Analysis of virus/host interactions at the molecular level. Course material is based on recent research publications.
Prerequisite: BCH210H1/242Y1/310H1/321Y1; BIO349H1/MGB311Y1; MBY378H1. (Note: BIO 351Y1 is not an acceptable equivalent to MBY378H1)
Recommended preparation: IMM334Y1/335Y1


MBY444H1
Environmental Microbiology 39L

Microorganisms normally exist in mixed communities whose composition and activity reflect the physical and chemical status of each particular niche. The structural analysis, nutrient cycling, and dynamics of microbe-microbe interactions in terrestrial, freshwater, and marine ecosystems are explored. The role of microorganisms in bioremediation is examined.
Prerequisite: MBY377H1 or permission of instructor
Recommended preparation: BCH210H1/242Y1/310H1/321Y1


MBY445H1
Genetic Engineering for Prevention and Treatment of Disease 39L

Current approaches to gene therapy including design of virus-based vectors for delivery and expression of effector genes. Emphasis on the use of retrovirus-based strategies for prevention and treatment of HIV infection.
Prerequisite: BIO349H1/MBY378H1/MGB311Y1


MBY450H1
Current Methods in Molecular Microbiology 78P

A laboratory course focussing on the use of molecular techniques to study microorganisms and their interactions with the host.
Prerequisite: MBY377H1, 378H1; MBY376H1/MGB312H1; MGB430H1 or permission of instructor


MBY480H1
Vaccines and Vaccination 39L

Analysis of infectious disease vaccines; past, present and future, with an emphasis on molecular aspects. Special topics include: molecular basis of pathogenicity; vaccination strategies; genetically engineered vaccines; DNA vaccines; modulation of the immune response by vaccine adjuvants; adverse effects of vaccines.
Prerequisite: MBY377H1, 378H1
Recommended preparation: IMM334Y1/335Y1




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