PCL299Y1
Research Opportunity Program

Credit course for supervised participation in faculty research project. See page $$ for details.

PCL301H1
Introduction to Pharmacology: Pharmacokinetic Principles (formerly part of PCL360Y) 39L, 13T

Topics include absorption, distribution, biotransformation, elimination, calculation of dosages, variability in drug response and adverse drug reactions.
Prerequisite: BIO250Y, CHM240Y, and permission of Department

PCL302H1
Introduction to Pharmacology: Pharmacodynamic Principles (formerly part of PCL360Y) 39L, 13T

Topics include biological action of drugs on membranes, enzymes, receptors, neural and hormonal systems, transmission and modulation.
Prerequisite: BIO250Y, CHM240Y, and permission of Department

PCL362H1
Introductory Toxicology 26L

Toxicological problems encountered in animals and humans; biochemical mechanisms and clinical factors of toxicological significance; models of drug-related diseases.
Prerequisite: BIO250Y, CHM240Y, and permission of the Department
Recommended Co-requisite: BCH310H, JLM349H, PCL360Y

PCL363H1
Principles of Pathobiology I 26L

Pathological changes brought about by foreign compounds; application of pathology to the detection of toxic and carcinogenic actions.
Prerequisite: BIO250Y, CHM240Y, and permission of the Department

PCL364H1
Principles of Pathobiology II 26L

Principles of pathobiology with emphasis on inflammatory and cardiovascular responses to tissue injury and foreign compounds.
Prerequisite: BIO250Y, CHM240Y, and permission of the Department

PCL470Y1
Systems Pharmacology 78L

Concepts of the properties of drugs and chemicals and the mechanisms of their interaction with living systems and their constituent parts. Pharmacology of nervous, cardiovascular, renal, respiratory, gastrointestinal and endocrine systems; endogenous compounds; chemotherapy.
Prerequisite: BCH310H, JLM349H, PCL360Y, PSL302Y, and permission of Department

PCL471Y1
Pharmacology Laboratory 104P

Demonstrations, seminars, and laboratory exercises in selected areas of Pharmacology.
Prerequisite: BCH370H, PSL372H, PCL360Y and permission of Department (see NOTE below)
Recommended Co-requisite: PCL470Y

PCL472Y1
Project in Pharmacology

Research project with reading assignments and a final written report by special arrangement with professors in the Department of Pharmacology, and other associated Departments.
Prerequisite: Permission of Department (See NOTE below)

PCL473Y1
Interdisciplinary Toxicology 52L

Traditional and contemporary problems in toxicology: general aspects, methodology, nature of toxic damage, general biological problems, poisons, applications and social policies.
Prerequisite: BCH310H, JLM349H, PCL360Y, 362H, and permission of Department

PCL474Y1
Project in Toxicology

Research project with reading assignments and a final written report by special arrangement with professors in the Departments of Pathology, Pharmacology, Pharmacy and other associated Departments.
Prerequisite: Permission of Department (See NOTE below)

PCL475Y1
Neuropsychopharmacology 78L, 26T

Major neuro-psychiatric disease syndromes: clinical pathology and neuronal abnormalities; CNS drugs: theories and mechanisms of action.(Not offered in 1999-2000)
Prerequisite: Permission of Department

PCL481H1
The Molecular and Biochemical Basis of Toxicology 26L, 26T

The biochemical principles and molecular mechanisms underlying the toxicity of drugs and foreign agents. The sequence of events at the molecular level leading to impairment of cell function and the factors which determine and affect toxicity.
Prerequisite: BCH310H, JLM349H, PCL362H, 363H, and permission of Department