Key to Course Descriptions.

For Distribution Requirement purposes, all PHC courses are classified as SCIENCE courses.

| Course Winter Timetable |

PHC300Y1
Molecular Pharmacology [72L, 24T]

The molecular basis for the action of drugs is presented based upon the physicochemical nature of the drug and its target.
Prerequisite: CHM247H1/CHM249H1; (CHM220H1,CHM221H1)/CHM225Y1; BCH210H1

PHC320H1
Medicinal Chemistry [36L]

Modern discovery and synthesis of antibiotics, antineoplastics, antiviral and other therapeutic agents.
Prerequisite: CHM247H1/CHM249H1; BCH210H1

PHC330Y1
Pharmaceutics [72L, 24T]

The study of the science and technology underlying drug delivery are covered. The properties of different dosage forms and delivery routes are studied with an emphasis on oral and parenteral routes.
Prerequisite: CHM247H1/CHM249H1; (CHM220H1,CHM221H1)/CHM225Y1; BCH210H1

PHC331H1
Establishing the Bioequivalence of Pharmaceutical Products [32L]

Introduction to human clinical trial design for the demonstration of pharmaceutical bioequivalence of drug products. Students will learn the principles underlying the regulations and methods employed in bioequivalence studies.
Prerequisites: MAT135Y1, BCH210H1, CHM247H1/CHM249H1,
Pre- or co-requisite : PHC330Y1/PHM224Y

PHC340Y1
Pharmaceutical Chemistry Laboratory [24L, 72P]

The scientific basis and practical techniques relevant to modern pharmaceutical development.
Prerequisite: CHM247H1/CHM249H1; (CHM220H1,CHM221H1)/CHM225Y1; BCH210H1

PHC401H1
Drug Transport across Biological Membranes [24L]

The goal of this course is to provide students with knowledge of the molecular processes involved in drug transport across biological cell membranes with emphasis on their physiological and clinical significance.
Prerequisite: PHC300Y1, Permission of the Instructor

PHC430H1
Recent Developments in Dosage Form Design [24L]

Introduction to controlled drug delivery: Mechanisms and kinetics of controlled drug release. Fundamental theories and mathematical tools for the design of modern dosage forms. Development and applications of controlled drug delivery dosage forms.
Recommended: (PHC330Y1,PHC340Y1)/PHM224Y1, Permission of the Instructor

PHC431H1
Selected Topics in Drug Development [24L]

In-depth discussion of implementation of pharmaceutical sciences in drug development strategies. Students will apply fundamental principles of pharmaceutics and drug delivery to current problems in the pharmaceutical industry.
Recommended: (PHC330Y1,PHC340Y1)/PHM224Y1, Permission of the Instructor

PHC451H1
Radiopharmaceuticals in Diagnosis and Therapy [14L, 14P]

Presents use of radiopharmaceuticals in diagnosis and therapy, emphasizing those used in nuclear medicine procedures studying neurological, cardiovascular, pulmonary, gastrointestinal, haematologic, endocrine and bone pathology.
Prerequisite: (PHC330Y1,PHC340Y1)/PHM224Y1, Permission of the Instructor

PHC452H1
Selected Topics in Radiopharmaceuticals [14L, 12P]

Introduces nuclear pharmacy through the discussion of problems that explain the design, production, analysis, and the clinical use of radiopharmaceuticals. Topics introduced using group discussions and laboratory exercises.
Prerequisites: (PHC330Y1,PHC340Y1)/PHM224Y, Permission of the Instructor

PHC460H1
Fundamentals of Drug Discovery [24L]

Lectures by scientists from academia and industry, and student seminars based on journal articles dealing with strategies for discovering new drugs for therapy and diagnosis.
Prerequisites: BIO250Y1, PHC300Y1/PHM222Y1, Permission of the Instructor

PHC489Y1
Pharmaceutical Chemistry Research [144P]

This course will provide research experience under the supervision of a Departmental staff member. The goal is to deepen the student’s understanding of the scientific basis and practical techniques relevant to modern pharmaceutical development.
Prerequisite: Permission of the Department and the Project Supervisor