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CHM Chemistry CoursesCHM138H1 This course is an introduction to principles of structure and their relation to
reactivity with an emphasis on the chemistry of organic molecules. Included are: atomic
and molecular structure, stereochemistry, acid/base equilibria, functional groups, and
fundamental reactions of organic molecules with a mechanistic emphasis. This course is
recommended for students in life and health science programs. CHM139H1 This course is recommended for students in life and health science programs. Structure
of matter, gases, liquids and solids; phase equilibria and phase diagrams; colligative
properties; chemical equilibria; electrolyte solutions and electrochemistry; reaction
kinetics; introduction to thermodynamics. CHM151Y1 Strongly recommended for students interested in following specialist or major programs
in Chemistry, and/or whose fields of study include a substantial amount of chemistry. The
lecture course and lab provide an introduction to some of the exciting current areas of
chemistry. Topics include: lasers and spectroscopy, organic molecules, biological and
synthetic polymers, and materials with novel properties such as superconductors. CHM200Y1 Human beings are constructed physically of chemicals, live in a sea of chemicals and
are very dependent for their material quality of life on the modern chemical industry.
This course is especially for non-science students who wish to develop a better
understanding of the impact and importance of chemistry in industry, society and the
environment. The course should be of particular interest to students with interests in
economics, commerce, management, politics, psychology and teaching. CHM217H1 Introduction to classical and instrumental analytical chemistry. Scope of analytical
chemistry: statistical methods; signal response, sensitivity and limit-of-detection of
various techniques. Solution equilibrium applications: gravimetry, titrimetry, acid-base,
redox and complexometric processes. Absorption spectroscopy: Beer’s Law. CHM220H1 Introduction to thermodynamics; phase equilibrium, chemicals equilibrium,
electrochemistry; introduction to quantum mechanics and spectroscopy. (First offered in
2001-02) CHM222Y1 Energy principles governing chemical and biochemical processes; reaction rates and
mechanisms; photochemistry; spectroscopy. Examples to illustrate fundamental principles
are taken, as far as possible, from the life sciences. This course is specially designed
to meet the needs of students in the life sciences; its emphasis is on biological systems.
Note that CHM225Y is the recommended course for the
Biological Chemistry, Chemistry, Chemical Physics, and Chemistry and Geology Specialist
Programs. (Not offered after 2000-01) CHM225Y1 This course, which is directed to students in the Chemistry major and specialist
programs, parallels CHM 222Y with a greater emphasis on
mathematical and problem solving aspects. Topics: introductory thermodynamics, first and
second law and applications; non-ideal gases, chemical equilibrium; electrochemistry,
surface chemistry; chemical kinetics; introductory quantum mechanics; spectroscopy, and
molecular photophysics. CHM238Y1 The first part (with CHM338H) of a two-year sequence
in Inorganic Chemistry, designed to illustrate and systematize the rich variety of
structures, physical properties and reactions of compounds of the elements across and down
the Periodic Table. Introduction to structure, symmetry and bonding of molecules and
lattices; acid-base and redox reactions; d-metal complexes; systematic chemistry of metals
and elements of the s and p blocks; inorganic materials and solid state chemistry with
applications in advanced technologies. The laboratory runs weekly from January to April. CHM240Y1 The fundamentals of organic chemistry: structures and reactions of organic compounds.
Principles of mechanism, synthesis, and spectroscopy. The laboratory includes work on
separation, purification, synthesis, and the identification of compounds. (Not offered
after 2000-01) CHM247H1 The fundamentals of organic chemistry with a focus on major reactions of s organic
compounds.Included are principles of mechanism, synthesis, and spectroscopy. (First
offered in 2001-02) CHM248Y1 An in-depth survey of organic molecules and principles of their reactions. Emphasis is
on understanding the basics with respect to structure and bonding, and application of
reactions to the synthesis of medicinally and industrially important compounds. Continues
from CHM 151Y. CHM299Y1 Credit course for supervised participation in faculty research project. See page 42 for details. CHM310H Major chemical pollutants and their sources, the environmental reactions they undergo,
and how they become distributed throughout the environment. Focus is on the principal
routes of chemical and biological degradation of toxicants; oxidation, photodegradation,
hydrolysis, reduction, biotic metabolism, and microbial degradation. The principal
physical processes by which chemicals move, concentrate, and dissipate. CHM314Y1 Scope of instrumental analytical chemistry; Fourier transform IR absorption
spectroscopy; molecular luminescence; emission spectroscopy; mass spectroscopy,
electrochemical techniques; sensors; gas and high performance liquid chromatography;
instrument design principles and applications in industry and the environment. The
laboratory runs weekly from January to April. CHM325H1 This course is fashioned to illustrate how inorganic and polymer materials chemistry
can be rationally used to synthesize superconductors, metals, semiconductors, ceramics,
elastomers, thermoplastics, thermosets and polymer liquid crystals, with properties that
can be tailored for applications in a range of advanced technologies. Coverage is fairly
broad and is organized to crosscut many aspects of the field. CHM326H1 This course introduces the postulates of quantum mechanics to develop the fundamental
framework of quantum theory. A number of exactly soluble problems are treated in detail as
examples. Perturbation theory is introduced in the context of understanding many body
problems. Various applications to molecular spectroscopy and dynamics are covered in
detail. CHM328H1 In this continuation of CHM225Y, more advanced topics
in thermodynamics such as non-ideal effects are introduced. Statistical mechanics and its
application to chemical problems are introduced. Reaction dynamics are analyzed from a
fundamental perspective. CHM338H1 Further study of the structures, physical properties and reactions of compounds of the
elements with emphasis on the transition metals. Introductions to spectroscopy and
structural analysis, reaction mechanisms, d- and f- block organometallic compounds,
catalysis, structures of solids and bioinorganic chemistry. The weekly laboratory
demonstrates aspects of transition metal chemistry. CHM345H1 An overview of the preparation of various classes of organic compounds. Strategies and
tactics of synthetic organic chemistry using examples from natural product and drug
syntheses. C-C bond formation, functional group reactivity, structure, stereochemistry and
selectivity. (This course is not allowed for students in any of the Chemistry specialist
and major programs; they should consider CHM346H
instead.) CHM346H1 An overview of the preparation of various classes of organic compounds. Strategies and
tactics of synthetic organic chemistry using examples from natural product and drug
syntheses. C-C bond formation, functional group reactivity, structure, stereochemistry and
selectivity. (Students who are not in any of the Chemistry specialist and major programs
should consider taking CHM345H instead of this course.) CHM347H1 Structure, reactions, and preparation of metabolically important compounds based on
modern concepts of organic chemistry. Advanced stereochemistry, carbohydrate structure and
reactivity, amino acid and peptide synthesis, reactions of nitrogen heterocycles,
synthesis and analysis of nucleotide and phosphate esters, synthesis of drugs. CHM348H1 Analysis of structure and reactions of organic molecules in terms of physical
principles. Mechanistic principles of important classes of organic reactions. CHM379H1 Biological macromolecules; structure, function and catalysis in the context of
biological phenomena. This course extends principles learned in earlier chemistry courses
to the understanding of important biochemical phenomena. CHM398H0/399Y0 An instructor-supervised group project in an off-campus setting. See page 42 for details. CHM410H1 An analytical theory, instrumental, and methodology course focused on the measurement
of pollutants in soil, water, air, and biological tissues and the determination of
physical/chemical properties including vapour pressure, degradation rates, partitioning. CHM414H1 Current research in analytical chemistry with emphasis on rapidly emerging techniques.
Course topics chosen from biosensor technology, transducer theory and operation, device
design and fabrication, surface modification and methods of surface analysis, flow
injection analysis and chemometrics. CHM415H1 This course considers the chemistry occuring in the Earth’s atmosphere, with
emphasis on developing molecular-level understanding of the photochemistry, free-radical
kinetics, and heterogeneous chemistry that occurs. Topics include stratospheric ozone
depletioon, trace gas oxidation, urban air pollution, acid rain, and the connections
between aerosols and climate. CHM416H1 Principles of separation in analytical chemistry. Fractionation processes and solvent
extractions; theory of chromatography, retention time, column efficiency and resolution.
Principles of gas-liquid chromatography; instrumentation for gas chromatography. High
performance liquid chromatography - practice and equipment design. Ion exchange,
size-exclusion and affinity chromatography. Electrophoretic techniques. CHM418Y1 An experimental or theoretical research problem under the supervision of a member of
staff. Applications for enrolment should be made to the Department in the preceding
spring. CHM421H1 Reaction mechanisms; collision dynamics; theory of the rates of elementary processes;
introduction to complex reactions including nonlinear processes. CHM423H1 Applications of time independent and time dependent perturbation theory to atomic and
molecular problems; WKB approximation and the classical limit; the interaction of light
with matter; elementary atomic scattering theory. CHM426H1 Scope of polymer chemistry. Organic and inorganic polymers. Synthesis and
characterization of polymers. Polymers as advanced materials. Polymers in solution:
Flory-Huggins theory. Polymers in the solid state: crystalline and amorphous polymers, the
effects of the glass transition on polymer properties. CHM427H1 Ensemble theory in statistical mechanics. Applications, including imperfect gases and
liquid theories. Introduction to non-equilibrium problems. CHM428Y1 An experimental or theoretical research problem under the supervision of a member of
the Physical Chemistry staff. Enrolment in this course may be restricted and must be
approved by the Department. Applications for enrolment should be made to the Department in
the preceding Winter Session. CHM432H1 Structure, bonding, and reactions of organometallic compounds, with emphasis on basic
mechanisms, and industrial processes. Addition, metalation, substitution, elimination,
important catalytic cycles, electrophilic, and nucleophilic reactions are considered on a
mechanistic basis. Properties of s and p block organometallics. CHM434H1 The development of newer methods of synthesizing primarily inorganic solids, growing
crystals and depositing films that have properties tailored for particular uses. The
subject matter covers materials chemistry aspects of host-guest inclusion, self-assembling
frameworks, synthetic electrical conductors, nanochemistry, buckyballs, buckytubes,
biomineralization and biomimetics. The interrelationship to property and function is
critically examined and how these create opportunities for new materials applications and
technologies. CHM437H1 Essential elements in biology; naturally occurring and medicinal ligands; transport,
uptake and control of concentration of metal ions; physical methods of characterization of
metal binding sites. Roles of metal ions: as structural and signaling elements in
proteins, nucleic acids and DNA-binding complexes and proteins; as Lewis-acid centres in
enzymes; as carriers of electrons, atoms and groups in redox proteins and enzymes; as
sources of biominerals; as radiopharmaceuticals. CHM438H1 A four-week intensive laboratory course during the first half of the Fall Session.
Eight set experiments designed to illustrate one or more facets of synthetic,
spectroscopic and analytical studies in inorganic chemistry. Applications for enrolment
should be made to the Department in the preceding Winter Session. CHM439Y1 An experimental or theoretical research problem under the supervision of a staff
member. Applications for enrolment should be made to the Department in the preceding
Winter Session. CHM440H1 Overview of classes of molecules currently used in treatment of diseases. Within each
therapeutic area, representative drugs on the market are considered and their syntheses
discussed. Reactions taught in previous courses and new reactions are used. Students also
gain appreciation of the mode of action, discovery and development of drugs in the
pharmaceutical industry today. CHM441H1 Structure and stereochemistry determination using modern spectroscopic techniques. The
main focus of the course is on NMR spectroscopy (1H and 13C). Other spectroscopy
techniques are discussed briefly, including infrared, X-ray and mass spectral methods. The
approach taken emphasizes applications of these spectroscopic methods to organic problems. CHM443H1 Methods for the determination of organic reaction mechanisms. Computational
calculations; kinetic techniques; study of reaction intermediates; structure-reactivity
correlations; linear free energy relationships; medium effects; isotope effects; acid-base
catalysis. (Not offered in 2000-01) CHM447H1 Applications of organic chemistry and physical organic chemistry to the study of
biologically important processes. Kinetics and mechanisms of enzyme catalysis, chemistry
of co-enzymes, stereochemistry of biological reactions, biosynthesis of important
biological molecules. CHM449Y1 An experimental research problem under the supervision of a faculty member.
Applications for enrolment should be made to the Department in the preceding spring.
Projects in the areas of synthetic, physical and bio-organic chemistry are offered. |
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