| Course Winter Timetable |

BCH210H1
Introductory Biochemistry 39L

An introductory course in biochemistry covering proteins, enzymes, and metabolism. This course is intended for students who are NOT taking BCH242Y as part of their program. (First offered in Summer 2001)
Exclusion: BCH242Y/310H/320Y/321Y/CHM379H/361H(E)/312H(E)
Prerequisite: CHM138H, 139H

BCH242Y1
Biochemistry 78L

An introduction to biochemistry for students specializing in biochemistry and related specialist programs. The major topics include protein structure, enzyme mechanisms, carbohydrates, metabolism and bioenenergetics, lipids, membranes, structure of DNA and RNA. (Note: This course will be first offered in the 2001-02 academic year)
Exclusion: BCH210H/310H/320Y/321Y/CHM379H/361H(E)/312H(E)
Prerequisite: CHM138H, 139H

BCH299Y1
Research Opportunity Program

Credit course for supervised participation in faculty research project. See page 42 for details.

BCH310H1
Introductory Biochemistry

(formerly BCH320Y) 39L
An introductory course in biochemistry intended for students who are NOT taking BCH321Y as part of their program. The course is divided into three sections, covering proteins, enzymes, and metabolism.
Exclusion: BCH320Y/321Y/CHM379H/361H(E)/312H(E)
Prerequisite: BIO250Y, CHM240Y/248Y

BCH321Y1
Introductory Biochemistry 78L

An introductory course in biochemistry. Intended for students specializing in biochemistry and related programs, and requiring a more intensive background in chemistry than BCH310H.
Exclusion: BCH310H/320Y/CHM 379H/361H(E)/312H(E)
Prerequisite: BIO250Y, CHM222Y/225Y, CHM240Y/248Y

BCH370H1
Laboratory Course in Biochemical Techniques 13L, 39P

Techniques in biochemical research and analytical laboratories. Intended for students who are not proceeding further in biochemistry. (Enrolment limited)
Exclusion: BCH371H
Prerequisite: BIO250Y, CHM240Y/248Y
Co-requisite: BCH310H

BCH371H1
A Laboratory Course in Biochemistry 75P

An introduction to laboratory techniques of modern biochemistry. Experiments illustrate and develop the concepts described in BCH321Y, and prepare the student for advanced training in biochemical laboratory techniques. (Enrolment limited)
Exclusion: BCH370H
Prerequisite: BIO250Y, CHM222Y/225Y, CHM240Y/248Y
Co-requisite: BCH321Y

BCH421H1
Protein Structure and Function 26L

Elements of protein structure and conformations are presented, and their role in protein functions is discussed in detail. Proteins as enzymes are described, and the structures and functions of membrane proteins are discussed. Recent advances in protein engineering, and site-directed mutagenesis are presented. (Enrolment limited)
Prerequisite: BCH321Y/CHM379H

BCH422H1
Cell Surface Biochemistry 26L

Structure and biogenesis of cell surface membranes; relationship of structure to functional aspects of the cell surface, cell-cell interactions, transmembrane signals, hormone receptors, cell surface enzymes and transport.
Prerequisite: BCH310H/321Y

BCH423H1
Metabolic Enzymology and Control Mechanisms 26L

Mechanisms of control of mammalian intermediary metabolism. Kinetics of feedback, allosteric proteins and enzymes; control of carbohydrate, lipid, amino acid, and nucleotide metabolism; relationship between metabolism and cell growth. (Offered in alternate years)
Prerequisite: BCH321Y

BCH424H1
Bio-organic Mechanisms 26L

The application of mechanistic chemistry to enzyme systems. Catalysis, chemical model systems, coenzymes, metals, covalent catalysis. (Offered in alternate years)
Prerequisite: BCH321Y

BCH425H1
Biophysical Methods 26L

Theory and practice of modern biophysical techniques as applied in the study of structure and function of macromolecules; emphasis on protein X-ray crystallography, NMR, and other spectroscopic methods; discussion of selected examples.
Prerequisite: BCH321Y/CHM379H

BCH429H1
Metabolism and Physical Chemistry of Lipids 26L

Structure, chemistry, and occurrence in biological systems of glycerides, phospholipids, glycolipids, and sterols, and aspects of their metabolism. Physical chemistry of complex lipids, principles governing assembly into bilayer membranes, and methods for studying membrane structure. (Offered in alternate years)
Prerequisite: BCH321Y

BCH430H1
Nucleic Acid Biochemistry 26L

The objective of the course is to introduce students to the chemistry of nucleic acids and nucleo proteins and how structure affects their functions as the reservoir of genetic information and as structural elements in biological systems.
Prerequisite: BCH310H/321Y

BCH471Y1
Advanced Biochemistry Laboratory 168P

Experiments demonstrating modern concepts of biochemistry and molecular biology. (Enrolment limited)
Prerequisite: BCH321Y, 371H/Erindale CHM361H, 362H, 371H

BCH473Y1
Special Work in Biochemistry 154P

Research in a particular area of biochemistry, by arrangement with the Department and the instructor concerned.
Prerequisite: BCH321Y, 371H and permission of Department
Co-requisite: BCH471Y