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Pharmaceutical Chemistry Courses

Key to Course Descriptions.

For Distribution Requirement purposes, all PHC courses are classified as SCIENCE courses except for PHC470H1, which is a SOCIAL SCIENCE course.

Course Winter Timetable


PHC 300Y1
Molecular Pharmacology 78L, 26T

The molecular basis for the action of drugs is presented based upon the physicochemical nature of the drug and its target.
Prerequisite: CHM 247H1/249H1; (CHM 220H1,221H1)/225Y1; BCH 210H1


PHC 320H1
Medicinal Chemistry 39 L

Modern discovery and synthesis of antibiotics, antineoplastics, antiviral and other therapeutic agents.
Prerequisite: CHM 247H1/249H1; BCH 210H1


PHC 330Y1
Pharmaceutics 78L, 24T

The study of the science and technology underlying drug delivery are covered. The properties of different dosage forms and delivery routes are studied with an emphasis on oral and parenteral routes.
Prerequisite: CHM 247H/249H; CHM (220H1,221H1)/225Y1; PCL 201H1; BCH 210H1



PHC 340Y1
Pharmaceutical Chemistry Laboratory 26L, 78P

The scientific basis and practical techniques relevant to modern pharmaceutical development.
Prerequisite: CHM 247H1/249H1; (CHM 220H1,221H1)/225Y1; PCL 201H1; BCH 210H1


PHC401H1
 Drug Transport across Biological Membranes26L

The goal of this course is to provide students with knowledge of the molecular processes involved in drug transport across biological cell membranes with emphasis on their physiological and clinical significance.
Prerequisite: PHC300Y1, Permission of the Department



PHC 430H1
Recent Developments in Dosage Form Design 26L

Introduction to controlled drug delivery: Mechanisms and kinetics of controlled drug release. Fundamental theories and mathematical tools for the design of modern dosage forms. Development and applications of controlled drug delivery dosage forms.
Recommended: (PHC330Y1,PHC340Y1)/PHM224Y1, Permission of the Department



PHC 431H1
Selected Topics in Drug Development 26L

In-depth discussion of implementation of pharmaceutical sciences in drug development strategies. Students will apply fundamental principles of pharmaceutics and drug delivery to current problems in the pharmaceutical industry.
Recommended: (PHC330Y1,PHC340Y1)/PHM224Y1, Permission of the Department



PHC 450H1
Applications of Pharmaceutical Analysis in Pharmacy and Medicine 21L, 16P

Overview of methods of pharmaceutical analysis such as titrations, UV-visible, IR, NMR and mass spectroscopy, fluorescence, HPLC, GC, TLC, electrophoresis, blotting, immunoassays and radiometric methods. Regulatory aspects of drug product quality control are covered. Introduces applications in pharmacy, therapeutic drug monitoring, toxicology, forensic science, athletics and clinical laboratory medicine.
Prerequisites: PHC300Y1/PHM222Y, (PHC330Y1,PHC340Y1)/PHM224Y, Permission of the Department




PHC 451H1
Radiopharmaceuticals in Diagnosis and Therapy 14L, 14P

Presents use of radiopharmaceuticals in diagnosis and therapy, emphasizing those used in nuclear medicine procedures studying neurological, cardiovascular, pulmonary, gastrointestinal, haematologic, endocrine and bone pathology.
Prerequisite: (PHC330Y1,PHC340Y)/PHM 224Y1, Permission of the Department



PHC 452H1
Selected Topics in Radiopharmaceuticals 14L, 12P

Introduces nuclear pharmacy through the discussion of problems that explain the design, production, analysis, and the clinical use of radiopharmaceuticals. Topics introduced using group discussions and laboratory exercises.
Prerequisites: (PHC330Y,PHC340Y)/PHM224Y, Permission of the Department



PHC 460H1
Fundamentals of Drug Discovery 26L

Lectures by scientists from academia and industry, and student seminars based on journal articles dealing with strategies for discovering new drugs for therapy and diagnosis.
Prerequisites: BIO250Y1, PHC300Y1/PHM222Y1, Permission of the Instructor



PHC 461H1
Selected Topics in the Pharmaceutical Industry 26L

Introduces drug development from the perspective of the pharmaceutical industry. Describes key stages in drug development process; current issues facing industry and role of pharmacists and pharmaceutical scientists in the process. Lectures are given by specialists employed in the pharmaceutical industry and concepts covered in the lectures will be applied to in-class case studies.
Prerequisites : PHC300Y1/PHM222Y1, (PHC330Y1,PHC340Y1)/PHM224Y1, Permission of the Department



PHC 470H1
Global Pharmaceutical Policy: Power and Politics 26L

Introduces concepts and issues in international pharmaceutical policy. Emphasis placed on how governments in different jurisdictions manage their public health responsibilities, international obligations, and pressure from special interest groups in terms of pharmaceutical policy.
Prerequisite: Permission of the Department
This is a Social Science course.



PHC 489Y1
Pharmaceutical Chemistry Research 156P

This course will provide research experience under the supervision of a Departmental staff member. The goal is to deepen the student’s understanding of the scientific basis and practical techniques relevant to modern pharmaceutical development.
Prerequisite: Permission of the Department and the Project Supervisor